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A patient takes diphenhydramine for allergies and is prescribed zolpidem for sleep. What is the MOST important counseling point?
A. Take both together for better sleep
B. Avoid taking them together due to additive sedation
C. Take with food only
D. One cancels the other out
Both are CNS depressants → additive sedation risk (HIGH-YIELD interaction)
A prescription is written for propranolol. Which condition would be LEAST appropriate?
A. Hypertension
B. Anxiety
C. Asthma
D. Atrial fibrillation
C. Beta blockers can worsen asthma (bronchoconstriction)
A patient taking warfarin starts ibuprofen OTC. What is the PRIMARY risk?
A. Decreased BP
B. Increased bleeding
C. Increased glucose
D. Kidney stones
B. NSAIDs + anticoagulants = major bleeding risk
A drug ends in -prazole. Which mechanism is MOST accurate?
A. Blocks dopamine
B. Reduces stomach acid production
C. Increases insulin
D. Breaks down clots
B. Proton pump inhibitor → ↓ gastric acid
A patient is prescribed lisinopril + hydrochlorothiazide. Why combine these?
A. Same mechanism duplication
B. Different mechanisms for better BP control
C. One treats infection
D. Reduce cost only
B. ACE inhibitor + diuretic → synergistic BP control
A patient reports persistent cough after starting a BP medication. Which class is MOST likely?
A. Beta blocker
B. ACE inhibitor
C. Diuretic
D. Calcium channel blocker
B. ACE inhibitors → classic dry cough side effect
A medication is used for both seizures and mood stabilization. Which class fits BEST?
A. Anticonvulsant
B. Antacid
C. Antibiotic
D. Statin
A. Anticonvulsants (e.g., valproate) can treat both
A patient is prescribed metformin but reports GI upset. What is the BEST advice?
A. Stop immediately
B. Take with meals
C. Take on empty stomach
D. Double the dose
B. Taking with food reduces GI side effects
A drug ends in -floxacin. What should you expect?
A. Viral treatment
B. Bacterial infection treatment
C. Pain relief
D. Anxiety reduction
B. Fluoroquinolone antibiotic
A patient takes codeine and reports extreme drowsiness after drinking alcohol. Why?
A. Increased metabolism
B. Additive CNS depression
C. Reduced drug effect
D. Liver detoxification
B. Opioid + alcohol = dangerous CNS depression
A technician sees sertraline and phenelzine together. What is the concern?
A. Hypertension only
B. Serotonin syndrome
C. Kidney failure
D. Hypoglycemia
B. SSRI + MAOI = serotonin syndrome (life-threatening)
A patient asks what albuterol does. Best explanation?
A. Slows heart rate
B. Opens airways
C. Lowers glucose
D. Reduces acid
B. Bronchodilator → relaxes airway muscles
A patient takes atorvastatin. Which counseling point is MOST relevant?
A. Take only when needed
B. Monitor for muscle pain
C. Avoid all fluids
D. Causes sedation
B. Statins → risk of muscle toxicity (myopathy)
A drug class treats acid reflux quickly but short-term. Which is MOST likely?
A. PPI
B. H2 blocker
C. Antacid
D. Statin
C. Antacids → fast, short-term relief
A patient takes benzodiazepines long-term. What is a MAJOR concern?
A. Immediate overdose
B. Dependence and withdrawal
C. Infection
D. High cholesterol
B. Benzos → dependence risk
A medication increases urine output and lowers BP. Which class?
A. Antiviral
B. Diuretic
C. SSRI
D. Antipsychotic
B. Diuretics remove fluid → ↓ BP
A patient asks why antibiotics don’t work for colds. Best answer?
A. Too weak
B. Colds are viral
C. Need higher dose
D. Only for pain
B. Antibiotics treat bacteria, not viruses
A patient takes multiple antihistamines. What is MOST likely?
A. Increased alertness
B. Increased sedation
C. Lower BP only
D. No effect
B. Antihistamines → additive drowsiness
A prescription for ondansetron is filled after chemotherapy. Why?
A. Treat infection
B. Prevent nausea/vomiting
C. Reduce pain
D. Improve sleep
B. Antiemetic → chemo-induced nausea
A patient takes levothyroxine incorrectly. Which instruction is BEST?
A. Take with food
B. Take on empty stomach
C. Take at night only
D. Crush tablet
B. Take on empty stomach
A drug ending in -sartan is most similar to which class?
A. ACE inhibitors
B. NSAIDs
C. Antibiotics
D. Antifungals
A. ARBs → similar purpose as ACE inhibitors (BP control)
A patient on opioids needs counseling. Which is MOST important?
A. Take with alcohol
B. Risk of respiratory depression
C. Causes hypertension
D. Improves alertness
B. Opioids → suppress breathing (critical risk)
A patient asks why drug classes matter more than individual drugs. Best answer?
A. Easier memorization only
B. Helps predict effects across many drugs
C. Not important
D. Only for doctors
B. Classes help predict indication, MOA, side effects
A patient takes pseudoephedrine and reports jitteriness. Why?
A. CNS depression
B. Stimulant-like effect
C. Blood thinning
D. Sedation
B. Decongestants can stimulate CNS → jittery feeling
A patient is prescribed fluconazole. What infection is treated?
A. Bacterial
B. Viral
C. Fungal
D. Parasitic
C. Antifungal
A patient takes two drugs from same class unnecessarily. What is this called?
A. Synergy
B. Therapeutic duplication
C. Potentiation
D. Contraindication
B. Therapeutic duplication
A patient asks what happens if multiple BP drugs are combined incorrectly. Risk?
A. Hyperactivity
B. Excessive hypotension
C. Infection
D. Insomnia
B. Too much BP lowering → hypotension