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American radiologists
Leukemia, reduced life span
Atomic bomb survivors
Malignant disease
Radiation accident victims (e.g., Chernobyl)
Acute lethality
Marshall Islanders
Thyroid cancer
Uranium miners
Lung cancer
Radium watch-dial painters
Bone cancer
Patients treated with 131I
Thyroid cancer
Children treated for enlarged thymus
Thyroid cancer
Children of Belarus (downwind from Chernobyl)
Thyroid cancer
Patients with ankylosing spondylitis
Leukemia
Patients who underwent Thorotrast studies
Liver cancer
Irradiation in utero
Childhood malignancy
Volunteer convicts
Fertility impairment
Cyclotron workers
Cataracts
hydrogen
60.0%
oxygen
25.7%
carbon
10.7%
nitrogen
2.4%
calcium
0.2%
phosphorus
0.1%
sulfur
0.1%
trace elements
0.8%
water
80%
protein
15%
lipids
2%
carbohydrates
1%
nucleic acid
1%
other
1%
Purines
Adenine & Guanine
Pyrimidines
Cytosine & Thymine
Radiosensitivity Cells that Belong in HIGH
Lymphocytes, Spermatogonia, Erythroblasts & Intestinal crypt cells
Radiosensitivity Cells that Belong in INTERMEDIATE
Endothelial cells, Osteoblasts, Spermatids, Fibroblasts
Radiosensitivity Cells that Belong in LOW
Muscle cells & Nerve cells
Muscle Abundance
43%
Fat Abundance
14%
Organs Abundance
12%
Skeleton Abundance
10%
Blood Abundance
8%
Subcutaneous tissue Abundance
6%
Bone marrow Abundance
4%
Skin Abundance
3%
High: 2-10 Gyt (200-1000 rad)
Lymphoid tissue (effect: atrophy - shrink triggered by cell death)
High: 2-10 Gyt (200-1000 rad)
Bone marrow (effect: Hypoplasia - underdevelop lack cell growth)
High: 2-10 Gyt (200-1000 rad)
Gonads (effect: atrophy - shrink triggered by cell death)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Skin (effect: Erythema - abnormal redness due to increase blood flow)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Gastrointestinal tract (effect: Ulcer - sores in stomach caused by bacteria)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Cornea (effect: cataract - clouding of eye = blurry vision)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Growing bone (growth arrest - stopping/slowing bone growth due to damge in epiphyseal plate)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Kidney (effect: nephrosclerosis - hardening of kidney arteries due to hypertension)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Liver (effect: ascites - build up of fluid caused by scarred liver)
Intermediate: 10โ50 Gyt (1000โ5000 rad)
Thyroid (effect: atrophy - shrink triggered by cell death)
Low: >50 Gyt (>5000 rad)
Muscle (effect: Fibrosis - build up collagen caused by scarring/hardening/thickening of tissue
Low: >50 Gyt (>5000 rad)
Brain (effect: necrosis - cell death caused by lack of blood flow)
Low: >50 Gyt (>5000 rad)
Spinal (effect: transection - dividing/cutting an organ, nerve, tissue
25 MV x-rays
LET: 0.2 RBE: 0.8
60Co gamma rays
LET: 0.3 RBE:0.9
1 MeV electrons
LET: 0.3 RBE:0.9
Diagnostic x-rays
LET: 3.0 RBE: 1.0
10 MeV protons
LET: 4.0 RBE: 5.0
Fast neutrons
LET: 50.0 RBE:10
5 MeV alpha particles
LET: 100.0 RBE: 20
Heavy nuclei
LET: 1000.0 RBE: 30
Threshold dose of Whole Body | effect: death
2 Gyt (200 rad)
Threshold dose of Whole Body | effect: Hematologic depression
250 mGyt (25 rad)
Threshold dose of small field | effect: skin erythema
2 Gyt (200 rad)
Threshold dose small field | effect: Epilation
3 Gyt (300 rad)
Threshold dose of Whole body | effect: Chromosome aberration
50 mGyt (5 rad)
Threshold dose of Local tissue | effect: Gonadal dysfunction
100 mGyt (10 rad)
Prodromal Period
>1 Gyt
Latent Period
1-100 Gyt
Hematologic
2-10 Gyt (mean survival time/days: 10-60)
Gastrointestinal
10 - 50 Gyt (mean survival time/days: 4 -10)
Central Nervous System (CNS)
>50 Gyt (mean survival time/days: 0-3)
LD50/60 (Gyt) of Pig after Whole-Body Radiation Exposure?
2.5 Gyt
LD50/60 (Gyt) of Dog after Whole-Body Radiation Exposure?
2.8 Gyt
LD50/60 (Gyt) of Human after Whole-Body Radiation Exposure?
3.5 Gyt
LD50/60 (Gyt) of Guinea Pig after Whole-Body Radiation Exposure?
4.3 Gyt
LD50/60 (Gyt) of Monkey after Whole-Body Radiation Exposure?
4.8 Gyt
LD50/60 (Gyt) of Opposum after Whole-Body Radiation Exposure?
5.1 Gyt
LD50/60 (Gyt) of Mouse after Whole-Body Radiation Exposure?
6.2 Gyt
LD50/60 (Gyt) of Hamster & Goldfish after Whole-Body Radiation Exposure?
7.0 Gyt
LD50/60 (Gyt) of Rat after Whole-Body Radiation Exposure?
7.1 Gyt
LD50/60 (Gyt) of Rabbit after Whole-Body Radiation Exposure?
7.3 Gyt
LD50/60 (Gyt) of Gerbil after Whole-Body Radiation Exposure?
10.5 Gyt
LD50/60 (Gyt) of Turtle after Whole-Body Radiation Exposure?
15 Gyts
LD50/60 (Gyt) of Armadillo after Whole-Body Radiation Exposure?
20 Gyt
LD50/60 (Gyt) of Newt after Whole-Body Radiation Exposure?
30 Gyt
LD50/60 (Gyt) of cockroach after Whole-Body Radiation Exposure?
100 Gyt
Expected Days of Life Lost in Being male rather than female
2800
Expected Days of Life Lost in Heart disease condition
2100
Expected Days of Life Lost in Being unmarried
2000
Expected Days of Life Lost in One pack of cigarettes a day
1600
Expected Days of Life Lost in Working as a coal miner
1100
Expected Days of Life Lost in Cancer condition
980
Expected Days of Life Lost in 30 pounds overweight
900
Expected Days of Life Lost in Stroke
20
Expected Days of Life Lost in All accidents
435
Expected Days of Life Lost inService in Vietnam
400
Expected Days of Life Lost in Motor vehicle accidents
200
Expected Days of Life Lost in Average occupational accidents
74