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Genetic Predisposition to asthma + allergy + AD (exaggerated skin and mucosal reactivity in response to environmental stimuli)
Describe the Atopy Triad (Presentation of Atopic Dermatitis)
Chronic
Atopic dermatitis can be describes as ____________ (acute/chronic)
True
(True/False) Atopic dermatitis is a condition in which relapsing inflammation of face, inside of knees, elbows, collar of neck
Atopic Dermatitis
Dx Criteria of _________________ is described as:
Itchy skin + >/= 3 of the following
- Onset <2yrs of age
- Hx of skin fold involvement
- Hx of generally dry skin
- Hx of atopic disease in 1st degree relative <4yrs
- Visible flexural dermatitis or on cheeks/forehead or outer limbs in <4ys
False
(True/False) Atopic Dermatitis is a curable disease
Hydrocortisone
What OTC can provide relief from itching and inflammation of atopic dermatitis
zinc & titanium
What two ingredients in sunscreen should be avoided in those with atopic dermatitis?
True
(True/False) Bathing is OK but only for 3-5 min and application of moisturizer within 3 min after
7
Hydrocortisone cream in the treatment of atopic dermatitis should be used for no more than ____ days
Cream
(Cream/Ointment) Seeking something with moderate moisturizing and that absorbs well into the skin
Ointment
(Cream/Ointment) Greasy + Occlusive, good choice for severely dry skin
True
(True/False) Oral probiotics have shown some evidence at decreasing the severity of atopic dermatitis
2
Pharmacists should refer anyone, for atopic dermatitis, under the age of _____
Refer
(Treat/Refer) Patient presents with atopic dermatitis presenting only in skin folds.
Dry skin
What is the most common cause of pruritus especially in the winter months
emollients
Non-pharm treatment of dry skin involves proper use of ______________ and modification of bathing practices
True
(True/False) Dry skin can be treated by drinking at least 8oz glasses of water daily
Urea, lactic acid or hyaluronic acid
What three pharmacologic ingredients may be proven helpful in severe cases of dry skin?
Ammonium lactate 12%
Moisturizer containing _____________________ help skin that is cracked or fissured
keratin
Alpha-hydroxyl acids help restore normal ___________ layer
Hydrocortisone ointment
May apply __________ ______________ to decrease inflammation and itching for dry skin
colloidal oatmeal
Some bath oils are combined with _________ ____________ to reduce itching
False
(True/False) Bath oils are highly effective for helping with dry skin
glycerin
This type of soap cleanser has a higher oil content and is thought to be less drying
Cetaphil or pHisoDerm
What two bath cleansers are mild and available if patient has been told to avoid soaps (minimize lipid layer loss)
Emollients
This bath product is an occlusive agents that leave an oily film on the skin trapping in moisture. Petrolatum containing ointments
Moisturizers
This bath product is available as lotions, creams, ointments, butters.
Either oil-in-water or water-in-oil emulsions
humectants
This bath product may include glycerin, propylene glycol, phospholipids
Draw water into top layers of skin
Urea
This is a mild keratolytic and increases water uptake (used in the treatment of dry skin)
Urea
Patient has dry crusted, necrotic tissue, what OTC product would you recommend?
Alpha-hydroxy acids
The lactic acid included increases hydration with this product
Hydrocortisone
this is the only steroid available OTC
IND: temporary relief of itching and inflammation
3-4x/d application/intermittent courses
Pramoxine, lidocaine and benzocaine
Name the 3 anesthetic options to help reduce the itching of dry skin
Oral
(Topical/Oral) Diphenhydramine may be considered if dry skin is severe
gels
If recommending ______ or lotions for dermatitis in hair-bearing areas, keep in mind that gels can be very drying if used for prolonged periods
Lotions then creams
What should you try for moderate dryness
Ointments
What should you use if extremely dry or cracked skin? (Avoid in skin folds due to potential maceration)
3-5 minutes
In the treatment of dandruff, how long should medicated shampoos be left in contact with skin prior to rinsing?
2-3 times per week for 2-3 weeks, then once weekly or every other week
What is the frequency of medicated shampoos for the treatment of dandruff?
Seborrheic dermatitis
Presentation: inflammation generally occurring in scalp, face and trunk areas
- red, scaly, itchy rash
- more severe in winter and emotional stress influenced
dandruff
chronic inflammatory condition, excessive scaling of scalp, itching is common
Psoriasis
Presentation: chronic inflammatory disease
- psychologic stress, UV exposure common triggers
- Elbows, knees, lumbar back, scalp, etc.
Treat
(Treat/Refer) Psoriases has mild presentation
nonresidue shampoo (J&J Baby shampoo)
What is the first line treatment for scaly dermatoses
Pyrithione Zinc
This anti-fungal agent may be used in the treatment of scaly dermatoses
- reduces yeast count in the scalp and skin
Ex: DHS Zinc, Head & Shoulders Dandruff Shampoo
Selenium Sulfide
this anti-fungal agents may be used in the treatment of scaly dermatosis...
- more effective with longer contact time
- may discolor blond, gray or dyed hair
Ex: Selsun Blue Shampoo, Head & Shoulders Intensive Treatment shampoo
Ketoconazole
this anti-fungal agents may be used in the treatment of scaly dermatosis...
- used to treat dandruff or Seborrheic dermatitis of the scalp
Shampoo twice per week x4 weeks, at least 3 days b/w treatments (apply once weekly to maintain control)
What is the treatment dosing of Ketoconazole
Cytostatic agents
These agents slow epidermal cell replication
Coal Tar
This Cytostatic agent cross links DNA and slows excessive skin cell growth
True
(True/False) Coal tar causes increased sensitivity to the sun
Keratolytic agents
These agents help loosen and lift keratin layers but are very slow acting (weeks to see improvement)
Salicylic Acid
This keratolytic agent... decreases skin pH and helps moisturize keratin layer
Ex: X-Seb shampoo, Sebulex shampoo, Sebulare lotion
Sulfur
This keratolytic agent... increases skin sloughing
Ex: Sulray, Sulfoam shampoo
Topical hydrocortisone
What can you choose for Seborrheic dermatitis with inflammation unresponsive to medicated shampoos
Irritant
____________ (Irritant/allergic Contact Dermatitis):
Diaper rash, jobs involving work around water or irritating chemicals
*usually dry or macerated, painful, cracked, inflamed skin
allergic Contact
____________ (Irritant/allergic Contact Dermatitis):
Most common is poison ivy/oak/sumac followed by metal allergies, then latex
*usually papules, blisters, inflamed and swollen skin, and EXTREME itching
mild or hypoallergenic soap
What is general treatment for irritant contact dermatitis
False
(True/False) Topical corticosteroids are OPTIMAL treatment for irritant contact dermatitis
EmollientS
This pharmacologic treatment for contact dermatitis can provide moisture to top layer of skin and serve as a protectant from irritants
Urushiol
Allergic contact dermatitis is typically caused by this plant based oil/resin
(found in poison ivy, poison oak, poison sumac, other plants)
urushiol
this type of induced dermatitis has blisters form later and affected area begins to crust over as it heals, unwashed hands, clothing, etc may transfer the antigen and new areas show up
False
(True/False) The liquid from blisters (in allergic contact dermatitis) contains the antigen and thus may cause the inflammation to spread
Mild
(Mild/Severe) Poison Ivy/Oak/Sumac Dermatitis:
Linear streaks, swollen eyelids common as many rub their eyes
Severe
(Mild/Severe) Poison Ivy/Oak/Sumac Dermatitis:
Extensive body involvement, edema of face and limbs, eyes may swell shut
IvyBlock
What is the only FDA approved barrier application for the prevention (PRE-EXPOSURE) of allergic contact dermatitis
Anesthetics, antihistamines or antibiotics
What three component is of ointments and creams should be avoided in the treatment of itching in contact dermatitis (especially NEOMYCIN)
True
(True/False) Oral antihistamines are OK to use for itching in allergic contact dermatitis
Prednisone
What the most common Rx prescribed for itching/allergic contact dermatitis
Astringents
If allergic contact dermatitis is weeping, what can be considered (ex: aluminum acetate - Burow's solution - witch hazel or calamine)
Hydrocortisone
This is the most effective OTC for inflammation in Allergic contact dermatitis
2 weeks
If allergic contact dermatitis is present for over ____ ________ =REFER patient
Gels
This product has easy application and rapid absorption however, some contain alcohol which may sting/burn (not a great option for open wounds)
Creams
This product is best for open weeping lesions and tend to be more drying
ointments
This product holds moisture within the skin and is effective on dry/cracked skin
False
(True/False) Ointments are able to be applied to open lesions and don't trap bacteria
sprays
this is the easiest form for application and allow for even distribution without touching the affected area
Tecnu and Zanfel
List the two OTC products that can be used for Post Exposure of Urishiol Induced allergic dermatitis.
Colloidal Oatmeal, Ivy Dry Cream (Camphor, menthol, zinc acetate), IvyBlock Lotion (Benzyl Alcohol, SDA Alcohol, Bentoquatam)
List common ingredients for poision ivy treatment
Pyrithione Zinc, Selenium Sulfide, Ketoconazole
List the 3 products for the treatment of scaly dermatoses that specifically have anti-fungal properties
Permethrin
Which Lice treatment does NOT require re-treatment unless active lice is found 7-10 days after initial treatment
Synergized pyrethrins
Which lice treatment REQUIRES re-treatment
Wet
Permethrin, in the treatment of lice, requires application to _______ (dry/wet) hair
Dry
Synergized Pyrethrins, in the treatment of lice, requires application to _______ (dry/wet) hair
Benzoyl peroxide
What is the primary pharmacologic treatment of acne?
False
(True/False) In the treatment of acne, one should start at the highest dose of Benzoyl peroxide for maximum effect
45
Sunscreen has the rule of ______
DEET
What is the primary insect repelent discussed
False
(True/False) Increased concentration of DEET works better overall and has longer duration
Refer
(Refer/Treat) Patient presents with a spider bite
True
(True/False) No wart products are 100% effective
apply and remove q 48 hours (2 days)
What is the SIG for Plaster Pads (wart treatment)?
Max 2x/d, allow to harden
What is the SIG and 1 key counseling point for Collodion (wart treatment)?
apply at HS (8hours) remove in AM
What is SIG for Karaya Gum-Glycol (wart treatment)?
Corns
(Corns/Calluses) Sharply defined margins + central core
Calluses
(Corns/Calluses) Broad base + uneven borders
Salicylic Acid
What is the primary pharmacologic treatment for corns/calluses
True
(True/False) If patient has DM or has poor blood circulation they should NOT be treated with salicylic acid for corns/calluses