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Hyperthyroidism
excessive activity of the thyroid gland
Concerns with hyperthyroidism:
adverse interaction with Epinephrine
life threatening arrhythmias
congestive heart failure, hypertension, angina, MI
thyrotoxic crisis
Dental management of hyperthyroidism:
avoid surgery
avoid epinephrine
monitor BP
treat infections with Ab
___ may be associated with hyperthyroidism, which would complicate dental procedures... this is rare though
Thrombocytopenia (excessive bleeding)
Thyrotoxic crisis, also called thyroid storm, has a ___
high mortality rate
What are some signs and symptoms of thyrotoxic crisis?
◦ Restlessness
◦ Very high fever
◦ Severe tachycardia
◦ Pulmonary edema
◦ Tremor, sweating, stupor
◦ Coma and death
What should you do if patient is going through a thyrotoxic crisis?
seek medical assistance ASAP
monitor vital signs
wet, ice packs
CPR, if needed
Generally speaking, if hyperthyroidism is well controlled, what can you do in dental office?
routine dental care
What are some oral manifestations of hyperthyroidism?
osteoporosis
periodontal disease
caries
premature loss of baby teeth; early eruption of permanent teeth
early jaw development
Hypothyroidism
underactivity of the thyroid gland
Concerns with hypothyroidism:
avoid surgery
treat infections aggressively
avoid/limit sedatives, depress, narcotics
myxedematous coma is a feared (rare) AE
Myxedematous Coma
life-threatening complication of long-term hypothyroidism; hypothermia, hypotension, lactic acidosis, dehydration, epileptic seizures, bradycardia
What should you do if patient has myxedematous coma?
seek medical aid
cover patient to conserve heat
CPR
Generally speaking, if hypothyroidism is well controlled, can you conduct routine dental treatment in office?
yes
What is congenital hypothyroidism syndrome called?
cretinism
= severe intellectual disability
= may need assistance with personal hygiene
Cretinism: Oral Manifestations in Kids
thick lips
enlarged tongue
delayed eruption of teeth
malocclusion
hoarse cry
Cretinism: Oral Manifestations in Adults
enlarged tongue
hoarse speech
puffy face
dry skin
coarse hair
Adrenal Insufficiency
condition in which the adrenal glands underproduce necessary hormones
(Addison's)
If a patient has Addison's, how should dental treatments be managed?
dental routine treatment should be deferred until patient is stabilized with corticosteroid therapy
Why do you need steroids, again?
Patients with Addison's disease lack the ability to naturally produce cortisol, the hormone the body relies on to manage physical and emotional stress. Because dental appointments induce stress, patients often need a temporary, pre-appointment "stress dose" of corticosteroids to prevent a life-threatening medical emergency known as an adrenal crisis.
Addison's Disease: Oral Manifestations
abnormal pigmentation
delayed healing
infection
Hyperadrenalism
excessive activity of one or more adrenal glands
(Cushing's)
Cushing's Syndrome: Dental Problems/Concerns
no specific ones!
just may need to modify due to possible symptoms of Cushing's, such as hypertension, diabetes, ulcers, etc.
Diabetes Mellitus
insulin is not secreted adequately or tissues are resistant to its effects
What test screens diabetic patients?
A1C
What are some common symptoms of diabetes mellitus?
polydipsia, polyuria, polyphagia, weakness
What A1C determines that you have diabetes?
over or equal to 6.5
A1C (HbA1c) measures what, in particular? Hint: beyond blood glucose levels
nonenzymatic glycosylation of hemoglobin - IRREVERSIBLE
Irreversible??
yes! once RBC has sugar attached to it, it will always have it.. until it dies/is replaced
Therefore, A1C reflects glucose levels in the blood over ___
the preceding 2-3 months (RBC lifespan)
not current, necessarily!
In health, patients should have A1C levels less than ___
5.7%
In well controlled diabetes, the level should stay below ___
7%
If diabetes is UNCONTROLLED UNCONTROLLED, A1C levels hit as high as ___ in some cases
20%
ABSURD
Glucometer
device for measuring blood glucose levels from a drop of blood obtained by a fingerstick
need to do ahead of dental appointment
Under ___ mg/dL means hypoglycemic, maybe due to taking too much insulin
70
under 70 = sweat, tremble
under 40 = convulsions, coma
under 20 = brain damage, death
What do you do in dental office?
defer elective tx or give carbs then proceed
Over ___ mg/dL means patient must take their insulin... blood glucose levels are spiking
200
What should you do in dental office?
defer tx, maybe give hypoglycemic
if very high, refer to physician
What are some potential issues with dental care of uncontrolled diabetic patients?
infection
poor wound healing
What are some complications of chronic diabetes?
CV issues
eyes — blindness
kidneys — renal failure
nervous system — peripheral neuropathy
What if diabetes is well controlled, what can dentist do?
all procedures can be performed without special precautions
One form of dental tx that should definitely be delayed if diabetes is not contemporarily controlled is ___ care
prosthodontic
Which appointments are best for diabetics?
morning
patient should take Insulin dosage and eat a normal meal before appointment
A dentist should always have ___ available in office, just in case
sugar
If extensive oral surgery is needed for a diabetic, a dentist should ___
consult MD
Do diabetics need antibiotic prophylaxis when undergoing extensive oral surgery?
maybe, if their diabetes is 'brittle'
What is insulin shock?
hypoglycemic reaction caused by taking excess of insulin —> too much glucose out of blooddstream
Signs of mild insulin shock:
◦ Hunger
◦ Weakness
◦ Tachycardia
◦ Pallor
◦ Sweating, skin wet and cold
◦ Paresthesias occasionally
Signs of moderate insulin shock:
◦ Incoherence
◦ Uncooperative
◦ Belligerence
◦ Lack of judgment
◦ Poor orientation
Signs of severe insulin shock:
◦ Unconsciousness
◦ Tonic/clonic movements (seizures)
◦ Hypotension
◦ Hypothermia
◦ Rapid thready pulse
If insulin shock occurs ...
terminate dental tx
place patient in comfy position upright
assess basic life support & monitor vitals
if conscious, give sugar
if unconscious, place patient in supine position with legs up — give glucose paste to buccal mucosa, no liquids!!! — and call 911
What is a popular drug that can cause hyperglycemia?
corticosteroids
Diabetes: Oral Manifestations
accelerated periodontitis
xerostomia = increased dental caries
poor healing, infection
traumatic ulcers
oral candidiasis
neuropathies
mucormycosis
Mucormycosis
type of fungal infection
associated with diabetes and HIV
feelings of numbness, but not pain
treated with amphotericin B
30-50% chance of mortality... very severe iinfection — fungus eats at bone and invades system