Degeneration

Aging

Gradual decline in the body’s ability to maintain homeostasis & repair itself

Cellular senescence

Cells stop dividing in response to various stressors

Human health span

The years lived in good health free from chromic disease or disability

Degeneration

Loss of function in cells, tissues, or organs over time

Atrophy

Gradual decrease in size of cell, tissue, or organ that has already reached its mature size

DNA & protein damage

(mutation & misfolded proteins)

Reduced Repair

Cellular & tissue levels

Mitochondrial decline

Energy drops → fatigue & organ dysfunction

Oxidative Stress

Free radicals accumulate, & antioxidant defenses weaken

Free radicals

Usable molecules that can damage DNA & proteins

Antioxidants

Help neutralize free radicals & reduce damage

Atherosclerosis

Degenerate disease of the arteries