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Total and irreversible cessation of all metabolic processes
Death
Directional occurrence of rigor from face to feet
Nysten's Law
Dying condition; dying
Moribund
Semi-convulsive twitches which often occur before death
Death Struggle
Death of the entire body
Somatic Death
Period immediately before somatic death. Sequence of steps as an expanding inability of the body to sustain the physiologic and metabolic process for life
Agonal Period
Occurrences in a sequence of events that are a function of time without oxygen: 1. cerebral cortex, 2. midbrain, 3. brain stem
Brain Death
Irreversible somatic death - cessation of simple body processes, organs no longer function
Biological Death
Individual cells die, process may continue for hours after somatic death
Postmortem Cellular Death
Brain and nervous cells -> 5 min
Muscle cells -> 3 hours
Cornea cells -> 6 hours
Blood cells -> 6 hours
Progression of Cellular Death
Agonal period
Somatic death
Clinical death
Brain death
Biological death
Postmortem cellular death
Stages of Death
(Physiology) The normal degeneration and death of living cells (as in various epithelial cells); antemortem, physiological death of cells of the body followed by their replacement
Necrobiosis
Pathologic death of cells or tissue as a result of disease
Necrosis
When spontaneous respiration and heartbeat irreversibly cease
Clinical Death
Death Is a:
Process, not a moment in time
1. Temp changes
2. Circulatory changes
3. Moisture changes
4. Trans-location of microorganisms
Changes During the Agonal Period
Decrease in body temperature immediately before death
Agonal Algor
Increase in body temperature immediately before death
Agonal Fever
Settling of blood into the dependent tissues before death. Due to the slowing of circulation, prior to death
Agonal Hypostasis
Change from a fluid into a thickened mass, clotting and congealing, prior to death
Agonal Coagulation
Opening of the pores in the walls of capillaries as the body attempts to get more oxygen to tissue and cells
Agonal Capillary Expansion
1. Cessation of respiration
2. Cessation of circulation
3. Muscular flaccidity
4. Changes in the eye: clouding of cornea, loss of luster and conjunctiva, flattening of the eyeball, dilated and unresponsive pupil
5. Postmortem lividity
6. Rigor mortis
7. Algor mortis
8. Decomp
Signs of Death
Agonal algor
Agonal fever
Temperature Changes
1. Agonal hypostasis
2. Agonal coagulation
3. Agonal capillary expansion
Circulatory Changes
1. Agonal edema
2. Agonal dehydration
Moisture Changes
Increase in amount of moisture or fluids in tissues and body cavities due to disease or agonal capillary expansion
Agonal Edema
Decrease in amount of moisture or fluids in tissues and body cavities due to disease or capillary expansion
Agonal Dehydration
Movement of microorganisms from one area of the body to another due to capillary permeability changes
Results from organisms no longer being restricted
Movement established by hypostasis, entering circulatory system, or natural mobility features
Movement from intestinal areas to the blood vascular system
Also known as agonal translocation
Translocation of Microorganisms
Physical changes
Chemical changes
Postmortem Changes
Brought about by the 'forces of nature' and create changes in the physical state of the body and its tissues
Postmortem Physical Changes
Cooling of the body to the temperature of the surrounding environment
Algor Mortis
Gravitation of blood and body fluids to dependent areas of the body
Hypostasis
Postmortem intravascular blood discoloration brought about by hypostasis
Liver Mortis
Loss of moisture from the body's surface due to the surrounding atmosphere
Dehydration
Thickening of blood primarily due to loss of liquid portion to tissue spaces
Increased Viscosity of Blood
Relocation of microorganisms in the body due to cessation of natural activities
Endogenous Invasion of Microorganisms
Brought about by chemical activity and result in the formation of new substances
Postmortem Chemical Changes
Temporary rise in body temperature after death
Postmortem Caloricity
Shift from slightly alkaline to acidic during rigor, then back to alkaline for decomposition
Change in Body pH
Natural body process causing postmortem stiffening of body muscles
Rigor Mortis
Color change due to heme seeping into body tissues from hemolysis
Postmortem Stain
Compounds breaking down into simpler substances by enzymes
Decomposition
Factors originating within the body
Intrinsic Factors
Factors from the body's surrounding environment
Extrinsic Factors
Body parts closest to the ground
Dependent Parts
Pale areas due to inhibited blood movement
Contact Palor
Liver Mortis Also Known As
Postmortem Lividity or Cadaveric Lividity
Cells drawing moisture from surroundings
Imbibition
Thick, viscous clumps formed by blood elements
Sludge
Solid portion: made up of blood cells
Liquid portion: what the cells are suspended in
2 Portions of Blood
Produces tissue gas
Embalmer's Nightmare
Clostridium Perfingens
Sum of all chemical reactions within the cell
1. Anabolism - building phase
2. Catabolism - breakdown phase
Metabolism
Relaxation of muscles immediately after death
Primary Flaccidity
Occurs after rigor mortis has left the body
Muscles return to a state of limpness and flaccidity
Secondary Flaccidity
Digestion of cells or tissues by the cell's own enzymes
Autolysis
Organic compounds with an amino group; derivatives of ammonia
Amines
Smelly breakdown products of protein putrefaction
- Alkaline substances
- Foul odor
Ptomaines
Decomposition of proteins by enzymes from anaerobic bacteria
Putrefaction
Decomposition of proteins by enzymes from aerobic bacteria
Decay
Speeds up chemical reaction rate
Catalyst
Chemical bonds break and new bonds form
Transition State
Glucose breakdown process
Fermentation
Forms from postmortem body fats hydrolysis
Adipocere
1. Carbs
2. Soft proteins
3. Fats
4. Hard proteins
5. Bones
Order of Decomp of Bodily Compounds
1. Color
2. Odor
3. Skin slip
4. Gases
5. Purge
Signs of Decomp
Greenish discoloration over right lower quadrant of abdomen
First Color Change in Death
Outer skin layer weakens due to autolysis in deeper layers
Desquamation (Skin Slip)
Evacuation of gases, liquids, and semisolids from body orifice
Purge
Stethoscope, Ophthalmoscope, Electroencephalogram, Electrocardiogram, Evoked Response
Expert Tests of Death
Listen for Breath/Heart Beat
Inexpert Tests of Death
What does the term extrinsic mean?
- external to the body
(to the outside of the body)
What does the term intrinsic mean?
- inside the body
Using a fluid with hypertonic qualities helps...
- us eliminate moisture.
Using a hypotonic solution can help...
- avoid dehydration.
Using a low index fluid can help...
- embalm jaundiced bodies without turning them green.
Using a fluid with humectant qualities can help...
- us add or retain moisture.
Using a hypertonic solution can help...
- us reduce excess water / edema.
Using cold/cool water when mixing fluids can help...
- avoid clotting blood
Algor mortis is a ___________ change to a dead body.
- physical
Dehydration is a __________ change to a dead body.
- physical
Hypostasis is a __________ change to a dead body
- physical
Livor mortis is a __________ change to a dead body.
- physical
Increased blood viscosity is a ___________ change to a dead body.
- physical
Bacterial translocation is a __________ change to a dead body.
physical
Algor Mortis (the post-mortem cooling of the body to the surrounding temperature)
- slows the onset of rigor mortis and decomposition; keeps blood in a liquid state and aids drainage.
Dehydration
increases the viscosity of the blood; may retard decomposition (putrefaction)
the liquid portion of the blood is being absorbed into the body; causes a resistance to blood flow and fluid distribution.
Increased Blood Viscosity
bacteria may move from the intestines to other areas of the body; this may speed decomposition.
Bacterial Translocation
Rigor mortis is a __________ change in a dead body.
- chemical
Decomposition is a __________ change in a dead body.
- chemical
Post-mortem stain is a __________ change in a dead body.
- chemical
Post-mortem caloricity is a _________ change in a dead body.
- chemical
Shift in the body pH is a _________ change in a dead body.
- chemical
makes features and body difficult to set; extravascular resistance to injection and an increased preservative demand; changes muscular firmness
Rigor mortis (the post-mortem stiffening of the body by natural causes)
color changes, skin slips, purge, gas and distension; poor distribution of solution; increased preservative demand; rapid swellings in the affected areas.
Decompostition
cannot be removed by embalming, but can be bleached; increased preservative demand; areas will turn grey after embalming.
Post-mortem stain
the body has lost its ability to cool itself; causes a temporary rise in body temperature; speeds rigor mortis and decomposition.
Post-mortem caloricity
Shift in body pH
interferes with fluid reactions.
The first time period of embalming analysis is...
prior to embalming