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Blood transfusion WW1
method of replacing lost blood in injured soldiers
Early problem
blood quickly clotted making transfusions difficult
Clotting issue
blood would thicken and block flow between donor and patient
Anticoagulant discovery
sodium citrate used to stop blood clotting
Sodium citrate
chemical that prevents blood from clotting during storage
Richard Lewisohn
helped introduce safe anticoagulant use in transfusions
Blood storage improvement
allowed blood to be kept for short periods before use
Direct transfusion method
blood passed directly from donor to patient
Indirect transfusion method
blood stored and then given to patient later
Donor requirement
healthy soldiers or volunteers needed to donate blood
Blood typing discovery
helped match donor and patient blood groups
ABO blood groups
classification system for human blood compatibility
Importance of matching blood
prevents clumping and death during transfusion
Karl Landsteiner
discovered blood groups and improved transfusion safety
Blood banks WW1
not fully developed but early systems began to form
Geoffrey Keynes
developed portable blood transfusion equipment
Portable transfusion kits
allowed blood to be used closer to battlefield
Franz Grobbel
developed early blood transfusion techniques in Germany
Shock treatment WW1
transfusions helped treat blood loss from injuries
Haemorrhage
severe blood loss from wounds
Effect of blood transfusion
increased survival rates of injured soldiers
Battlefield injuries
shrapnel and bullets caused major blood loss
Timing of transfusion
early transfusion improved chances of survival
Transport of blood
had to be carefully handled to avoid contamination
Sterilisation importance
equipment had to be clean to prevent infection
WW1 medical advancement
transfusion became more reliable over time
Medical limitation WW1
lack of refrigeration made storage difficult
Use in hospitals
transfusions often done in casualty clearing stations
Emergency transfusion
used for severely wounded soldiers in shock
Blood donor pools
soldiers from same regiment often used as donors
Effect on surgery
allowed more complex operations due to blood replacement
Medical innovation WW1
war accelerated development of transfusion techniques
Survival rate impact
more soldiers survived severe injuries than in earlier wars
Key problem solved
blood loss was one of the main causes of death in WW1