Drug Metabolism & Interactions

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Last updated 5:03 PM on 6/16/26
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8 Terms

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Carbamazepine
Induces CYP450 enzyme
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Rifampin
Induces CYP450
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Phenobarbital
Induces CYP450
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Enzyme inducers
Lower the effectivener of the co administered drug
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Enzyme inhibitors
Raise the toxicity of the drug
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Cimetidine
Is a CYP450 inhibitor
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CYP 450
They are liver enzymes that oxidises the drugs Phase 1 metabolism
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Tetracycline interaction with milk
Tetracycline shouldn't be taken with milk, milk binds to the tetracycline and absorbtion decreases. The calcium in milk binds to the tetracycline and they clump in gut