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Nurse Responsibilities
Interpret orders, prepare/administer meds, teach patient, document, evaluate response.
What medication task can student nurses NOT do?
Transcribe orders or take verbal/telephone orders.
3 Medication Names
Chemical, generic, trade/brand.
Chemical name
Describes molecular structure of the drug.
Generic name
Official drug name used in references like CPS.
Trade/Brand name
Manufacturer’s name for the medication.
Drug classification
Describes what the drug does and its effect on the body.
Example of multiple drug classifications
Aspirin = analgesic, antipyretic, anti-inflammatory.
Types of drug preparations
Tablet, capsule, liquid, patch, cream, etc.
Critical rule for drug preparations
Always administer medication in prescribed form.
Pharmacokinetics
What the body does to the drug.
4 parts of pharmacokinetics (ADME)
Absorption, distribution, metabolism, excretion.
Absorption
Movement of drug from entry site into bloodstream.
First-pass effect
Oral drug metabolized before reaching circulation.
Bioavailability
Amount of drug reaching target cells.
Distribution
Movement of drug through bloodstream to tissues.
Albumin and drugs
Only unbound drugs are active.
Who is at risk for low albumin toxicity?
Older adults, liver disease, malnutrition.
Metabolism
Breakdown of medication into inactive form mainly in liver.
Risk with poor liver function
Drug accumulation and toxicity.
Excretion
Drug leaves body through kidneys, lungs, skin, bowel, mammary glands.
Main organ for excretion
Kidneys.
Half-life
Time for 50% of drug to be eliminated.
Therapeutic effect
Desired effect of medication.
Side effect
Predictable unintended effect.
Adverse effect
Severe harmful effect requiring drug stoppage.
Toxic effect
Harm from accumulation, overdose, or impaired metabolism.
Idiosyncratic reaction
Unpredictable drug reaction.
Allergic reaction
Immune response to medication.
Signs of allergic reaction
Rash, hives, itching, rhinitis.
Anaphylaxis
Life-threatening allergic reaction causing bronchoconstriction and circulatory collapse.
Nursing action for anaphylaxis
Stop drug, notify prescriber, initiate protocol.
Medication interaction
One drug alters another drug’s effect.
Polypharmacy
Use of multiple medications.
Who is most affected by polypharmacy?
Older adults.
Synergistic effect
Combined drugs produce greater effect together.
Example of synergistic effect
Alcohol + CNS depressants.
Why is grapefruit juice dangerous with statins?
Blocks CYP3A4 causing toxic drug levels.
Medication response goal
Maintain constant therapeutic blood level.
Onset
Time when drug effect begins.
Peak
Highest drug concentration.
Trough
Lowest drug concentration.
Duration
Length of time drug effect lasts.
Medication order
Legal written direction by prescriber.
Routine order
Ongoing medication order.
Stat order
Immediate one-time order.
Single order
One-time scheduled order.
Standing order
Condition-based order.
PRN order
As-needed order requiring nursing judgment.
7 required parts of a medication order
Patient name, date/time, drug, dose, frequency, route, prescriber signature.
Medication reconciliation
Creating accurate medication list during admission, transfer, discharge.
Purpose of medication reconciliation
Prevent errors and polypharmacy.
Nurse’s role in medication administration
Know drug, assess safety, administer correctly, monitor, document, report reactions.
10 Rights of medication administration
Right client, medication, dose, route, time, documentation, reason, refuse, education, evaluation.
Right client
Use 2 identifiers like name and DOB.
Right dose
Usually no more than 3 tablets.
Right time
Give within ±30 minutes depending on policy.
Right documentation
Never sign before giving medication.
Right to refuse
Patient can refuse medication.
What should nurse do if patient refuses medication?
Ask why, educate, notify prescriber, document.
Client education must include
Reason, action, side effects, precautions.
Right evaluation
Assess effectiveness, side effects, adverse reactions, interactions.
3 Checks of medication administration
First check, second check, third check.
First check
When removing medication from drawer.
Second check
After preparation.
Third check
Before returning or administering medication.
During all 3 checks verify
Right client, medication, dose, route, time.
Also check during 3 checks
Allergies, expiry, transcription.
3 A’s at bedside
Allergies, assessment, armband.
Medication administration considerations
Keep meds packaged until bedside, never leave unattended, stay until swallowed.
Best patient position for oral meds
Upright to prevent aspiration.
Oral medication route
Most common and easiest route with slower onset.
Contraindications for oral meds
Nausea/vomiting, GI obstruction, gastric suction, unconsciousness, decreased LOC, increased RR.
Medications that should NOT be crushed
Enteric-coated, sustained-release, sublingual/buccal meds.
Liquid medication measuring under 10 mL
Use oral syringe.
Liquid medication measuring 10 mL or more
Use medication cup.
How to pour liquid meds
Label facing palm and measure at meniscus.
Scored tablets
Only tablets that may be safely split.
Important oral med rule
Avoid mixing medications together.
Best fluid for medications
Water.
Safe medication disposal for needles
Yellow sharps container.
Safe medication disposal for medications/vials
Blue pharmaceutical container.
Federal medication regulation agency
Health Products and Food Branch (HPFB).
HPFB responsibilities
Assesses safety, approves drugs, licenses production sites, inspections, recalls.
Food and Drug Act regulates
Drug composition, strength, purity, packaging, labeling, storage.
Products covered by Food and Drug Act
Drugs, herbs, natural health products.
Provincial regulatory body in Manitoba
College of Registered Nurses of Manitoba (CRNM).
CRNM role
Sets standards for safe medication practice.
Examples of CRNM standards
Entry-level competencies, scope of practice, RN authorized prescriber.
Negligence
Failure to meet standard of care.
Example of negligence
Not checking patient identification.
Site-level medication policies
Hospital policies that follow federal and provincial standards.
Examples of site-level policies
Auto-stop antibiotics and high-risk med restrictions.
Legal aspect of medication administration
Nurse is responsible even if order came from provider.
What unsafe orders should nurses question?
Incomplete or unsafe orders.
Can medication administration be delegated?
No.
Standards of practice responsibilities
Interpret orders, reconcile meds, administer, monitor, report errors.
Safety culture
Focuses on reducing system errors and interruptions.
Examples of interruption reduction
“Do not disturb” zones and medication prep areas.
Medication error
Preventable event causing inappropriate therapy or harm.