Catalyic Strategies - Biochem chpt7

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Last updated 5:48 PM on 6/3/26
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5 Terms

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covalent catalysis

the active site has a reactive group that temporarly covalent bonds to part of the substrate

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general acid-base catalysis

a group other than water donates or accepts a proton

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metal ion catalysis

metal ions help make nucleophiles stabilize negative changes on intermediates, or bride E to S position the substrate

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catalysis by approximation

the enzyme holds two substrates close together on one surface so they react faster

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transition-state stabilization

the enzyme binds the transition state even more tightly than the substrate