Peripheral Nerve Injury & Regeneration - Week 11

Which statement BEST defines peripheral neuropathy?

A general term describing pathology of one or more peripheral nerves

An occupational therapist notes sensory loss on the lateral forearm and lateral hand. Based on dermatomal distribution, which nerve root level is MOST likely involved?

C6

During nerve compression, which sensory modality is typically lost FIRST?

Conscious proprioception and discriminative touch

As nerve compression is relieved, patients often report paresthesias. What BEST explains this phenomenon?

Increased blood supply restoring nerve conduction

Which sensory modality returns LAST during recovery from nerve compression?

Conscious proprioception

Flaccidity following a peripheral nerve injury is BEST described as:

Decreased muscle tone resulting in weakness or paralysis

Which cell type is responsible for producing nerve growth factor (NGF) in the peripheral nervous system?

Schwann cells

A client with a median nerve compression would MOST likely present with which diagnosis?

Carpal tunnel syndrome

Which statement accurately compares regeneration in the PNS versus the CNS?

PNS regenerates more effectively due to Schwann cell NGF production

Normal peripheral nerve regeneration occurs at approximately what rate?

1 mm per day

Which autonomic changes are MOST characteristic of peripheral nerve injury?

Glossy skin, hair loss, and nail thickening

Complex Regional Pain Syndrome (CRPS) is BEST described as:

A chronic neurovascular condition involving autonomic dysfunction

An evidence‑based occupational therapy intervention for CRPS includes:

Mirror box therapy

Wrist and finger drop resulting from radial nerve compression is commonly associated with:

Saturday night palsy

Compression of the peroneal nerve is MOST likely to result in which gait abnormality?

Steppage gait

Which type of peripheral neuropathy involves bilateral damage to multiple peripheral nerves?

Polyneuropathy

Stocking‑and‑glove distribution sensory loss is MOST commonly associated with:

Diabetic polyneuropathy

Absence of deep tendon reflexes is a common finding in:

Peripheral neuropathy

Guillain‑Barré syndrome is characterized by:

Acute demyelination with symmetrical flaccid paralysis

Synkinesis following nerve regeneration MOST often occurs because:

Regenerating axons innervate inappropriate target tissues