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Thinking about mental illness throughout history - early on
Ancient Egyptians (6000-5000 BCE)
Largely equated mental, physical illness
But thought all illness was due to evil spirits
Classical Greeks (e.g., Hippocrates, 400 BCE)
Suggested treatments for “human conditions”, not just severe psychosis
But treatments included bloodletting, getting married
Thinking about mental illness throughout history - more modern
1500s
Mentally ill = witch
Best Case: chained up in an institution
Worst Case: killed
1700s
Some advocacy for humane treatment
1800s
Mental hospitals
Some were pretty nice
Thinking about mental illness throughout history - late 1800s
Big, Expected Problems
Nice asylums are expensive
Asylums were being overwhelmed
Late-stage syphilis patients
Asked to also take care of elderly dementia patients
Psychiatrists spent all their time managing asylums, not treating mental illness
As overcrowding reaches critical levels, mortality rates reach 5x general population
Thinking about mental illness throughout history - late 1800s-1950s
Serious thinking about treatments, not just confinement
Freud is thinking hard about counseling
Psychiatrists are trying out medical treatments
Unfortunately, many treatments are wacky, ineffective, or even harmful
Freud’s approach is based mostly on his intuition, not scientific evidence
Medical approaches are even worse
Inducing malarial fever
Inducing diabetic coma
Thinking about mental illness throughout history - modern times
Talk therapies grow up:
Still influenced by Freud’s interesting but non-scientific approach
But now based in serious experimental research
Freud - Importance of early childhood events “Subconscious” processes in the brain -
Talk-therapy as a treatment / cure
Medical approaches grow up:
Drugs targeting specific neurotransmitters
Depression (serotonin)
Anxiety (GABA)
Anti-psychotics (dopamine)
Talk Therapy - Psychoanalysis
Derived from Freud’s theory of personality
Aims to relieve subconscious “conflicts”
Methods:
Free-association
Dream interpretation
Analysis of “Freudian Slips”
Drawbacks:
Takes a long time (and money)
Probably not effective for serious disorders
Probably not more effective than any other therapy
Psychodynamic Therapy
Neo-Freudian”
Aims: To understand maladaptive behaviors by looking for themes across relationships in a person’s life
Therapist discovers negative behavior “themes”
Helps the patient to change
Behavior Therapies - counter-conditioning
Derived from classical conditioning
Ex: phobias
Counter-conditioning:
Pairing the trigger stimulus with a new response that is incompatible with fear (go to your happy place)
Over time, phobia weakens
Behavior Therapies - exposure therapies
Exposure Therapies:
Expose a person to the stimulus that causes anxiety, until they are no longer anxious
Behavior Therapies - systematic desensitization
Systematic Desensitization
Figure out what causes the anxiety and gently expose them to it.
Behavior Therapies - alcoholism
Aversive Conditioning:
Substituting a negative response for a positive response to a harmful stimulus:
Pairing alcohol with nausea can make alcoholics averse to drinking
Does it work?
33% after 3 years
Knowing actual cause of nausea may decrease effectiveness
Operant Conditioning
Recall:
OC can be used to “shape” behaviors
Step-by-step reinforcement of specific actions
Cat could escape from “puzzle” box
Locus of Control
How do you account for what happens in your life?
Why do good things happen to me?
Why do bad things happen to me?
Internal - in control of ones own actions
External - everything happens from luck or fate
Helplessness Experiment
In both animals and people, helplessness leads to depression
Experiment:
Group A: No shocks
Group B: Gets shocked, jumps away, repeat
Group C: Same shocks as Group B, but no control
Group C dogs “think”: I have no control over my life
Thoughts about Locus of Control
Similarly, people who think they are in control are happier:
Nursing home patients were given more control
93% reported positive changes to quality of life, compared to control group:
More alert
More active
Happier
Cognitive Therapies
Aim: Adjust a person’s maladaptive thinking style
Most people have “self-serving bias”:
Attribute Success to personal, internal factors
Attribute Failures to external factors
Depressed people may not exhibit SSB
Cognitive Therapy:
Teach depressed people to “reinterpret” events
Group/Family Therapy
Often problems are directly related to social interactions
Especially family interactions
Aim: Help family resolve conflicts more effectively
Rationale:
Solutions to family problems should involve whole family
Also, some therapy may benefit from support / knowledge of other people with similar problems (e.g., AA)
Does Therapy Work?
Therapy effectiveness is not easy to measure:
Patients often enter therapy when at their worst, and so they’re likely to get better (“regression to the mean”)
Clients develop a relationship with the therapist, want to believe the therapist is effective (cognitive dissonance?)
Not surprisingly, clinicians feel they are very effective (but may not feel the same way about other therapists)
Unusual Therapies
“Scared Straight”: Programs that take young people to jails to see what their future might be
Kids say it made a huge difference
Studies show: Kids are actually MORE likely to later wind up in jail
“Boot Camp” style programs:
No indication that they are effective
Untrained “counselors” have been implicated in abuse scandals
Alternative Therapies
Mostly untested, unknown effectiveness
When tested, most turn out to be ineffective or harmful
Does therapy work? - standard therapies
Legitimate, modern therapies have a relatively good record:
Average therapy patient does better than 80% of similar untreated control
Which therapies work?
Behavioral therapies:
Good for disorders with clear stimulus-response characteristics:
Phobias, Compulsions, Sexual Disorders
Cognitive Therapies:
Good for disorder that involved negatively-biased thinking
Depression, Anxiety
Many therapists combine BOTH approaches (“Cognitive-Behavioral Therapy”)
Psychopharmacology
Hugely influential, and helpful to many:
But…
Less effective than many believe
Controversial (may be vastly over-prescribed)
Antipsychotic drugs
Dopamine-blocking drugs reduce schizophrenia symptoms
Long term use can lead to Parkinson’s disease like symptoms (Parkinson’s disease is related to dopamine deficiency)
Side effects / difficulty determining proper dosage can make schizophrenics feel lousy, not take their medication
Antidepressant drugs
Mostly SSRIs:
S=Selective
S=Serotonin
R=Reuptake
I =Inhibitor
Works for many (41%), but so does placebo (31%)
Criticism of antidepressant drugs
Criticism:
Depression is not only biology
Biological effects interact with “social” factors
Interact?
Are caused by
Are increased / decreased by
Biology can be dominated by social factors
Often people are depressed for a reason
Prozac will not get you a better job / friends / life
“Talk” therapy is still, on average, most effective
Anti-anxiety drugs
Depress nervous system
Relieve fear-like symptoms of anxiety
Criticism:
Treat symptoms, but not underlying cause of anxiety
Considered by most addiction specialists to be “highly addictive”
Radical Therapies
Electroconvulsive therapy:
Electricity applied to Brain
Used for severe depression
Likely works by stimulating neuron growth in brain areas related to emotion regulation
Can cause memory loss
May be only effective treatment for some patients
Potential New Therapies
Repetitive transcranial magnetic stimulation
Painless magnetic field applied to surface of brain
Used for severe depression
Effectiveness not established
No known side-effects
Ketamine, psilocybin, Ecstasy, LSD, other psychedelics?
Therapist
Training, license, supervision, and experience of the therapist have little effect on patient outcomes
So, is all this training useless? No!
Hard to evaluate outcomes
Hard to equate “training”, “experience” across therapists
ALSO: Different therapists see very different patients
How are therapists trained?
Counselors: no training necessary.
Clinical, psychiatric social worker:
2 year MSW program + post graduate supervision
Clinical psychologist:
Ph.D. or Psy. D., research, assessment, therapy training, supervision, internship, postdoctoral training, state license
Psychiatrist:
MD + specialty, knowledge of pharmaceutical agents
Only therapist who can prescribe medications
The computer metaphor
Encoding: Information goes in
Storage (Short term, Long term)
Retrieval: Information is accessed later on
How is your memory NOT like a computer?
Memories can get details wrong; can forget.
Computers store exact copies.
Type 1 - sensory memory
Visual info
Iconic memory: Very short term photographic memory
How short? < 0.5 s
Sperling’s experiments:
Used arrays of letters
(1) Array pops up on screen
(1) Array disappears after a very short time
(1) Tone (high, medium, low) indicates recall line
If retention interval = 0 sec
Recall (from one line) = 3 letters = 100%
So, all 9 letters were still in memory
If retention interval = 1/2 sec
Recall (from one line) = 1 letter = 33%
So, only 3 letters (out of 9) were still in memory
Type 2 - working(short term) memory
Receives attended information from Sensory Memory
Holds, processes visual and auditory information
Coordinates with Long Term Memory
Experiment:
Subjects were asked to remember 3 consonants (e.g. GHJ)
Rehearsal was limited by a backwards counting task
After 3 sec., performance was at 50% correct
Type 3 - long term memory
Very high capacity
Memories are stored permanently
But memories interfere with each other
Forgotten information is not gone
It’s just inaccessible
Encoding
Getting info into your brain
Some encoding is automatic.
Spatial locations – where did you park your car?
Events – what did you do yesterday?
You don’t have to try to remember those things.
Other encoding requires effort
What we typically think of as “memory”
Learning the state capitals
Encoding and Sleep
Sleep is important for encoding information in LTM
Information presented:
just before sleep is remembered poorly
1 hour before sleep is remembered well
while sleeping is not remembered
Serial Position Effect
Remember first and last stuff really well and middle stuff not so well.
Have strategy in beginning and then so many words that begin to forget.
Levels of Processing
Semantic - actually understanding meaning; what you do with it.
Stays in memory longer and will be more robust.
Acoustic - is a bit less understanding
Visual - understanding meaning to the lowest capacity.
Chunking
Using existing memories to store more information per chunk
Test right away - 100%
Forgetting happens quickly and slowly later on.
When relearning, get better quickly but levels off as time goes down.
Encoding - best practice
Don’t make it easy
More difficult encoding leads to better learning
Performance: How you’re doing right now
Learning: How you’ll do in the future
An “expanding retrieval schedule” can help keep encoding difficulty high (which is a good thing)
Study until you can recall 100%
Wait 10 minutes
Study until you can recall 100%
Wait 30 minutes
Study until you can recall 100%
Wait 2 hours… and so on.
Ebbinghaus forgetting curve
During breaks, forgetting happens
How do you measure forgetting?
Had people encode nonsense syllables: VUT, GER, ROP…
Wait some time
Measured “savings on relearning”:
Savings = Original Learning Reps - Relearning Reps/Original Learning Reps
Savings on relearning
Forgetting is fast at first, then slow
You keep forgetting more, the longer you wait, but most of the forgetting happens early on
But each time you relearn, overall forgetting slows down
Context
Items presented together are associated in memory
Everything associated with an item is its “context”
Recall of context will cue recall of other information
Emphasizing different details can trigger memory of other different details
Forgetting - retrieval failure
Proactive Interference (acts forward in time):
Past learning interferes with new learning
Ex: Trying to learn new student names
Interference from previously learned students’ names impairs ability to learn new names
Retroactive Interference (acts backwards in time):
New learning interferes with already learned information
Ex: An actor learns lines for a new play
Interference from newly learned lines impairs ability to remember previously learned lines
Interference and sleep
You don’t forget as much while you’re sleeping
One theory: When you’re awake, there’s more interference
2 main types of long term memories
Explicit
Processed in hippocampus
Facts- general knowledge
Personality experienced events
Implicit
Processed by cerebellum
Skills - motor and cognitive
Classical and operant conditioning effects
Amnesia
Amnesiacs lose the ability to form new explicit memories
Can still form new implicit memories
The hippocampus
Neural center involved in forming explicit memories
Monkeys with surgically removed hippocampus lose memories formed in the last month
Won’t be able to form new memories
The cerebellum
Neural structure related to formation of implicit memories
People with damaged cerebellum may be unable to develop basic classical conditioned responses:
Forgetting - repressed memories
Memories for traumatic events
Cannot be recalled for long periods of time
Sometimes resurface in therapy
Little evidence they exist; Some evidence they don’t
Most memory researchers don’t believe in them
Retrieval from Long Term Memory
Memories of events are not only your encoded experience
Memories of events are a reconstruction, based on:
Some encoded facts about your experience
A lot of knowledge about how things probably were
What makes eyewitness testimony unreliable?
1) Leading questions
Police may supply information or presume facts:
“Did you see the gun?” (bad; assumes a gun) vs.:
“What did you see?” (good; no bias induced)
These subtle changes can alter memory
2) Focus of attention
Details that might be important later might seem unimportant at the time
3) Context/Arousal
Memory is most effective at moderate arousal levels
Arousal is part of “context”. If you’re calm at the time of the interview, context will be very different, recall is impaired
4) Overconfidence
Witnesses are often repeatedly questioned during trial prep
Recalling events many times gives the false impression that a memory is more reliable than it really is:
Best practice - cognitive interview
1) Mentally reinstate the context
2) Report all details, including “unimportant” details
3) Recount events from other perspectives
4) No leading questions
Cognitive Interview uses many concepts from class:
Reinstate context for accuracy
Vary the context for more information
Avoid contaminating the memory
Implanted Memories - Elizabeth Loftus
The “Lost in a Mall” Story
Had subjects read stories, most of which were true (from their own lives), one of which was plausible, but made up:
Subjects were later quizzed on events from the stories and asked to answer if these events were from their own lives
After repeated questioning about the stories (over days), subjects began to believe false events were real:
Source error - brought up in 1st interview not realizing that memorized from 1st interview instead of real life
Children as eyewitnesses
Social Aspect
Child’s desire to please the interviewer
Cognitive Aspect
Source errors - child often cannot distinguish whether they remember something, or were told something
Implanted memory - leading questions actually change child’s memory
Both also affect adults, but not as much
Children’s Suggestibility
Children repeatedly asked leading questions:
Can be convinced false events occurred
Refuse to believe something was made up, even after being told by the questioner how they were deceived
Experts on child behavior are unable to detect implanted vs. real memories from child’s report
By age 10, children are no more suggestible than adults
Take home point:
Because children can be victims of crime, it’s important that they be allowed to testify…
But, we must be careful because young children are more susceptible to memory manipulation
What is intelligence?
Brain Size / Body Mass predicts intelligence
So, for animals with the same body mass, Bigger Brain = Smarter Brain?
In some brain areas, more brain mass correlates with intelligence
Is intelligence just having a good brain?
No
Concept of “intelligence” varies across cultures
What our society values determines (to some extent):
What we choose to do
What we excel at
How our brains develop
General vs Specific Intelligence
General intelligence involves an overall enhancement in problem solving and reasoning skills.
But people can develop high performance in specific areas, such as (but not limited to): word fluency, memory, inductive reasoning, etc.
Savant Syndrome
Highly specific, enhanced ability
“Islands of Intelligence”
Sometimes associated with autism
Multiple Intelligences
Common types of savants:
- Music
- Drawing / painting
- Calendar calculating
- Languages
- Accurate perception of passing time
Emotional Intelligence
The ability to use / understand / manage
- Your own emotions
- Other people’s emotions
Brain damage can selectively impair Emotional Intelligence
The IQ Test
Q tests attempt to measure the “general” part of intelligence
What an IQ test SHOULDN’T do:
- Depend on culture, race, etc.
- Change with age
- Change with level of education
Binet’s mental age
Mental development trajectory is similar across children
Some progress more rapidly than others
Average score by age = mental age
Stanford-Binet IQ = Baby’s Mental Age / Real Age x 100
Modern IQ Tests for adults
IQ is measured relative to people of the same age
Population mean is set to 100
Standard deviation is set to 10
Correlations with IQ:
School grades
Yrs. of education:
Parent’s SES:
Job Performance
Husband + Wife:
Identical Twins
Good Social Skills
How to develop a good psych test
1) Standardization: Scores are “curved” so that mean, standard deviation are the same for every version of the test
Otherwise, scores may reflect difficulty of test, not intelligence
2) Reliability: If a test measures a stable characteristic of a person, it should give consistent, stable results.
A single person should get roughly the same score if:
They take 2 versions of the same test
The test is administered by different people
The test is given at two different times
3) Validity: Does your test actually measure intelligence?
Content Validity: Test covers relevant material
Predictive Validity: Test predicts future achievement
The Flynn Effect
Better…
- Test-taking skills?
- Nutrition?
- Environmental factors (mental stimulation)?
- Public education availability?
New results suggest the Flynn Effect may have stopped
What affects your IQ?
1) Age?
Not a lot. Relatively stable across 70 years
2) Genes? Yes.
3) Environment? Yes.
Over time genetic effects dominate environment:
Big controversy with IQ tests:
Do different races have different average IQs?
Answer? Yes
Why does race affect IQ scores?
Maybe:
- Biased test questions (probably small effect)
- Differences in education quality, SES, etc.
- Other environmental influences
No:
- Genetic differences
Measured IQ vs IQ
- “Measured IQ” = Score on an IQ test
- “IQ” = Actual measure of a person’s Intelligence
What affects your measured IQ?
At birth (equal):
White, black infants equal on infant intelligence measures
8th grade - end of high school:
Black students scores go down
White students scores go up
College (back to roughly equal):
Black students increase 4X white students
Gap narrows considerably
Great differences in quality of schooling
Public schools are funded through property taxes
On average, boys and girls are about the same
But at extreme scores, there are more boys
It is commonly believed that Girls + Boys differ by ability
Girls are appear to be better at:
- Spelling
- Verbal ability
- Remembering locations
- Touch, taste, odor sensation
- Math computation (adding up #s, etc.)
Boys appear to be better at this - math problem solving
Degrees of Intellectual Disability
Mild - may learn academic skills up to 6th grade level. Adults may, with assistance, achieve self-supporting social and vocational skills.
Moderate - may progress to second-grade level academically. Adults may contribute to their own support by laboring in sheltered workshops.
Severe - may learn to talk and to perform simple work tasks under close supervision but are generally unable to profit from vocational training.
Profound - require constant aid and supervision.
Intelligence extremes - high end
People with relatively high IQs:
Do not tend to be socially maladjusted
No more likely to have emotional problems
Geniuses
Sometimes defined as IQ > 140
People with very high IQs may feel isolated because set of “peers” is very small
If you have an IQ of 135 only 1 out of every 100 randomly selected people will be as smart or smarter than you
More likely to have social, emotional problems