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Engram
Physical representation of memory in the brain, encoded by changes in the neuronal connections during learning
Declarative memory
Type of long-term memory that involves conscious recollection of facts and events, crucial for learning new information
LTM
A type of memory that stores information for an extended period, allowing for retention and learning
STM
Limited capacity memory store that holds info temporarily for learning and immediate use
Episodic memory
A type of declarative memory that involves remembering specific personal experiences.
Procedural memory
A type on long term memory for skills and habits which are crucial for learning and performing tasks automatically
Long term potentiation
Strengthening of synaptic connections, a key mec for learning and memory formation
Long term depression
Weaking in synaptic connections which plays a role in refining neural circuits during learning
Synaptic plasticity
The ability of synapses to change in strength, which is essential for learning
Hebbian synapses
Genetic variations in the ApoE gene that can influence an individual's risk for developing Alzheimer's disease, which affects learning and memory
Sensitization
An increased response to a stimulus after repeated exposure, a simple form of learning in both humans and animals.
Habituation
The production of false or distorted memories, which can occur in individuals with memory impairments and affect their learning, common symptom in Korsakoff's syndrome
AMPA receptors
Programmed cell death, which is important for brain development and may play a role in synaptic pruning during learning
NMDA receptors
Unprogrammed cell death, which can occur due to injury or disease and may disrupt learning and memory processes in the brain
ApoE polymorphism
Synapses that strengthen when pre and post synaptic neurons fire simultaneously, key in learning and memory
Tau vs Amyloid beta proteins
Two proteins involved in the pathology of Alzheimer's disease, which can impair learning and memory by disrupting neuronal function
Confabulation
A decreased response to a stimulus after repeated exposure, a simple form of learning that allows organisms to filter out irrelevant stimuli.
Apoptosis
Glutamate receptors mediate fast synaptic transmission and play a role in synaptic plasticity and learning
Necrosis
Crucial for synaptic plasticity, learning, and memory formation, require both glutamate binding and post synaptic depolarization to activate
Korsakoff syndrome
Extensive brain damage – caused by prolonged thiamine (vitamin B1) deficiency
Thymine is crucial in glucose metabolism
Without glucose the neurons die or shrink
Epigenetic changes due to alcohol use
After adolescent alcohol use → decreased level of proteins for cognitive functions → increased vulnerability for psychiatric disorders
Environment and intelligence
quality of feedback for a child has an impact on their development
effect of environment enrichment → lack of stimulation leads to cognitive impairment
Environmental enrichment
increases dendritic branching & synaptic density, increase in neurogenesis, increase in neurotransmitter levels and receptor expression, improvement in cognitive performance
people with damage to their hippocampus…
Have trouble forming new long term declarative memories especially episodic memories
Working memory
Stores information that one is currently using, the cortex stores a working memory by occasional bursts of high frequency oscillations that alternate among many cells
High cortisol levels associated with prolonged stress…
damage cells in the hippocampus thereby impairing memory
reinforcement
a reinforcer is any event that increases the future probability of the response
punishment
an event that supresses the frequency of the response
equipotentiality
all parts of the cortex contribute equally to complex behaviours such as learning and any part of the cortex can substitute for any other
mass action
the cortex works as a whole, and more cortex is better
lateral interpositus nucleus (LIP)
one nucleus of the cerebellum, essential for learning
Anterograde amnesia
inability to form memories for events that happened after brain damage
retrograde amnesia
loss of memory for events that occurred before brain damage
semantic memories
memories on factual information