Behavioral Action of Drug: Exam 4 **

Which of the following drugs is/are FDA-approved to treat nausea and vomiting?

dronabinol (Mariol) nasilone (cesamet)

Is heroin the most dangerous opioid in the US?

no its fentanyl

Strong drug seeking behavior and planning ways to get more PCP is mediated by __________

increased dopamine in the dorsolateral prefrontal and anterior cingulate cortexes

If a person smoked marijuana with PCP, what is likely to happen to the marijuana's bioavailability?

there will be more cannabinoids in the system because there would be decreased metabolism of the marijuana

What is the result of this hippocampal down regulation when smoking marijuana?

impaired long term memory

Which of the following seems to have the lowest potential to cause physical dependency?

dimethyltrypatmine

People tend to build a rapid tolerance to LSD primarily because of down regulation of which receptor?

5HT-2A

Which of the following is considered an opioid but not an opiate?

methadone

Lemuel is found stumbling around his neighborhood naked and sweating. He seems "out of it" as he punches a guy walking his dog. He then runs onto the railroad tracks in front of a train shouting that he is invincible. What drug did he most likely just take?

PCP

Which of the following neurotransmitters often exerts it effects through retrograde transmission and is so lip soluble that it would seep through any vesicles trying to carry it, which is why neurons make it as needed make it as needed rather than storing it?

anandamide

What is primary psychoactive drug in mushroom tea?

psilocybin

Mandred has been suffering from pain due MS. Unfortunately he has no health insurance and can't get any medication for his pain other than ibuprofen and other over the counter (OTC) medications. But those OCT medications dont help his pain at all. However, he has a friend who can get him "non-prescription" drugs. Which of the following would be best for Manfred to help his pain?

marijuana

Nancy smokes K2 on weekly basis. K2 and other synthetic marijuana can cause similar effects to natural marijuana, such as relaxation and elevated mood. However, synthetic marijuana, including the K2 Nancy is using was banned in the US because it can also cause vomiting seizures paranoia and hallucinations. How does it cause there more severe side effects?

although marijuana can cause similar side effects at very high dose, synthetic marijuana is more likely cause to serve side effects because it binds more strongly for longer period of time to receptors and is much more potent so it is easier to overdose

Delysid was the trade name for what drug?

LSD

What is the primary psychoactive drug in the peyote that ben uses?

mescaline

What is the fastest way to get high from heroin?

smoking

which of the following would be an example of synesthesia from acid?

seeing colors when music is played

what is the primary neurtransmitter system that is implicated with hallucinations, such as psilocybin and mescaline?

serotonin

which of the following has been shown to be helpful in reducing psychotic symptoms decreasing seizures in some forms of epilepsy and relieving anxiety?

cannabidoil

____ is 50 times more potent than heroin and 100 times more potent than morphine

fentanyl

which of the following is a schedule II drug that is less potent than phencyclidine and is used as an anesthetic in children?

ketamine

Which drug is a partial opioid receptor agonist but has a much milder withdrawal symptoms than heroin and reduces cravings?

Buprennorphine

what is the primary psychoactive drug in ayahuasca?

DMT

PCP and ketamine work differently than other hallucinogens we studied. What is the mechanism of action for these two drugs?

NMDA receptor antagonism, Dopamine reuptake inhibition, and nicotinic receptor antagonism

Which tea starts to make the world feel like it is moving in waves?

mushrooms

Cyril is in a lot of pain. However, he does not want to take opioids. Which of the following is an non opioid reliever?

celecoxib (celebrex)

When detecting heroin use, the presence of ____________ would show the person used heroin and not poppy seeds

6-monoacetylmorphine

What drug did Dr. Timothy Leary use when he traveled to Mexico?

mushrooms

Huxley, Ginsberg, and Kesey all used what drug?

peyote

Which of the following drugs is currently the cause of the most OD deaths in the states?

fentanyl

Which drug is derived from a plant with naturally occurring psychedelic alkaloids that can cause dissociation, ataxia, neurotoxicity and prolonged lapse between ventricular heartbeats?

Ibogaine

which of the following is an accurate statement regarding tolerance to opioids?

1) cross tolerance to other opioids occurs for all opioids

2) tolerance can build up to such high levels in chronic uses that a dose that get same high dose could kill a non addict

Isaac is rushed to the hospital because he is overdosing. He is just barely breathing, has slurred speech, couldn't stand on his own, was unresponsive, had small pupils, and his skin was taking on a bluish hue. Which drug causes this?

heroin

Although PCP is very dangerous, when is it usually prescribed?

for use as a veterinary tranquilizer

Which of the following people is most likely to suffer from cannabinoid hyperemesis syndrome?

Bill, a 25 year old male who smokes marijuana everyday after to work to relax

Which of the following is the correct order from the most to the last of THC in cannabis sativa?

flower tops > bracts > leaves > steams > roots > seeds

_____ is low in psychoactive properties itself, can help treat symptoms of dragnet syndrome, and may protect against development of psychotic symptoms in people with psychosis that can be cause or exacerbated by THC.

cannabidiol

Which hallucinogen primarily affects k-opiod receptors and causes odd out of body experiences?

salvinorin A

Which drug causes withdrawal symptoms similar to nicotine and opioids?

marijuana

which of the following is the correct order from lowest to highest potential for physical dependency?

LSD, marijuana, alcohol, cocaine, heroin

There are 5 opium alkaloids. Which is the most abundant of these?

Morphine

What areas of the brain are implicated in rumination or letting the mind wander and having internal monologues and also in hallucinogenic mushrooms?

medial prefrontal cortex, posterior cingulate cortex, angular gyrus

Why does cannabis not have a significant drug-drug interaction as far as protein binding is concerned?

while most drugs bind to albumin, cannabis binds primary to lipoproteins

A bunch of friend are smoking together. Who's bioavailability of THC for each of these friends is highest?

1) Ronald is higher than Mary because he is a heavy user

2) since the whole group is smoking togehter, Francis and Steve have the highest because they each smoke an entire joint in one puff

waiver is very relaxed, happy, and social. He is in tune with smells, colors, and noises. He is eating a large bag of chips. what drug is he on?

marijuana

From which naturally occurring opiate alkaloid are drugs such as oxycodone and naltrexone synthesized?

thebain

which of the following is the correct sequences for the synthesis of heroin?

opium --> morphine --> heroin

which of the following drugs was synthesized from ergot?

LSD

which nerve fiber(s) carry the information that your finger was smashed by a hammer?

A delta

Chad use to smoke weed, snort coke, and drink. He quit all three a few months ago. Which of the following is most accurate about what is likely to happen when he starts smoking weed again?

when he smokes marijuana, the stimulation of cannabinoid receptors will cause him to crave coke and alcohol