snRNP maxing

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Last updated 12:03 AM on 4/27/26

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U1 snRNP

binds to the 5’ splice site in RNA (shown below)

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U2 snRNP

binds to the branch site and aligns it for the 1st splicing reaction

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U4 snRNP

binds to and sequesters U6 snRNP

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U5 snRNP

aligns the pre-RNA for the 2nd splicing reaction

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U6 snRNP

promotes catalysis of splicing reactions