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These flashcards cover key vocabulary and concepts related to the heart and circulation as discussed in the lecture.
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Functions of the circulatory system
Transporting nutrients, oxygen, hormones, and waste products throughout the body.
Pulmonary circuit
The system of blood vessels that carries blood between the heart and the lungs.
Side of heart that pumps for pulmonary circuit
The right side of the heart.
Systemic circuit
The system of blood vessels that carries blood between the heart and the rest of the body.
Side of heart that pumps for systemic circuit
The left side of the heart.
AV valves eversion prevention
The chordae tendineae and papillary muscles prevent eversion.
Flow of blood through heart and great vessels
Blood flows from the body into the right atrium, through the right ventricle to the lungs, and returns to the left atrium and left ventricle to be pumped to the body.
Three layers of blood vessels
Tunica intima, tunica media, and tunica externa.
First heart sound S1 (Lub) cause
Closure of the AV valves during ventricular contraction.
Second heart sound S2 (Dub) cause
Closure of the semilunar valves during ventricular relaxation.
Causes of valve closure
Pressure changes in the heart chambers.
Heart murmur
An abnormal heart sound often due to turbulent blood flow.
Term for a leaky valve
Regurgitation.
Term for a narrowed or stiff valve
Stenosis.
Cardiac cycle
The sequence of events in one heartbeat, including systole and diastole.
Systole
The phase of the cardiac cycle when the heart contracts and pumps blood.
Diastole
The phase of the cardiac cycle when the heart relaxes and fills with blood.
End-diastolic volume (EDV)
The volume of blood in a ventricle at the end of diastole.
End-systolic volume (ESV)
The volume of blood in a ventricle at the end of systole.
Connection of myocardial cells
Intercalated discs connect all myocardial cells.
Functional syncytium
A network of interconnected cells that function as a single unit.
Pacemaker of the heart
The sinoatrial (SA) node located in the right atrium.
Sequence of conductive tissues in the heart starting with SA node
SA node → atrioventricular node (AV node) → bundle of His → Purkinje fibers.
Secondary pacemakers
Atrioventricular (AV) node andbundle branches.
Pacemaker potential in SA node cause
Gradual depolarization due to sodium influx.
Three electrical events of cardiac muscle action potentials
Phase 0: rapid depolarization, Phase 1: initial repolarization, Phase 2: plateau phase.
Long refractory period in myocardial cells cause
Calcium influx during the plateau phase prevents premature contraction.
Importance of long myocardium refraction
Prevents tetany and allows effective pumping; seen as the baseline on EKG.
EKG definition
Electrocardiogram; measures the electrical activity of the heart.
P wave representation
Atrial depolarization.
QRS wave representation
Ventricular depolarization.
ST segment representation
The period between ventricular depolarization and repolarization.
T wave representation
Ventricular repolarization.
Cause of heart attack
Coronary artery blockage; ST elevation is a common indicator on EKG.
ST depression significance
May indicate ischemia or myocardial infarction.
ST elevation significance
May indicate acute myocardial infarction.
Layers of blood vessels
Tunica intima, tunica media, and tunica externa; tunica media is influenced by the autonomic nervous system.
Elastic arteries
Large arteries with high elasticity, found near the heart.
Capillaries
Tiny blood vessels that allow exchange of oxygen, nutrients, and waste.
Bulk of blood volume location
Primarily in the venous system.
Help veins return blood to heart
Skeletal muscle pump and respiratory pump.
Functions of lymphatic system
Transport lymph, provide immune responses, and return fluid to blood circulation.
functional syncytium
Atherosclerosis
A condition characterized by the buildup of plaque in arteries, leading to potential blockages.
LDL and HDL cholesterol
LDL (low-density lipoprotein) is 'bad' cholesterol; HDL (high-density lipoprotein) is 'good' cholesterol.
Ischemia definition
Insufficient blood flow to tissue due to blockage.
Infarction definition
Tissue death due to lack of blood supply.
Chest pain symptom
Angina.
Myocardial infarction (MI) cause
Plaque rupture followed by thrombosis at an atherosclerotic site.
Atherosclerotic process in vessel wall
Formation of fatty streaks that develop into plaques.
Arrhythmia definition
Irregular heart rhythm.
Bradycardia definition
Abnormally slow heart rate.
Tachycardia definition
Abnormally fast heart rate.