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Afferent somatosensory information_________.
travels from the sensory organs inward via the somatic nervous system.
Movement information
travels out of the central nervous system via a parallel efferent system.
Spinal Segment corresponds to a region of body surface
Dermatome
The motor cortex lies in the______________.
lobe, anterior to central fissure in brain
The sensory cortex lies____________.
posterior to the central fissure and extends into the parietal lobe
Layer IV (afferent) is relatively thick in the__________.
Sensory cortex
Layer IV (afferent) is relatively thin in the___________.
Motor cortex
Layer V (efferent) is relatively thick in the_________.
motor cortex
Layer V (efferent) is relatively thin in the_________.
sensory cortex
Lashley
Argued that movements must be performed as motor sequences, with the next sequence held in readiness while the ongoing one is under way
Motor Sequence
Movement modules are preprogrammed by the brain and produced as a unit
Prefrontal cortex
Plans complex behavior
Premotor Cortex
produces the appropriate complex movement sequences
Primary motor cortex
specifies how each movement is to be carried out
Primary Motor Cortex
Specializes in producing focal skilled movements, such as those of the arms, hands, and mouth
Species-typical behavior
Actions produced by every member of a species
Hess
Stimulated different areas within the brainstem to produce different species-specific behaviors
Cerebral Palsy
•Voluntary movements difficult to make, whereas conscious behavior controlled by the cortex may remain intact
•Caused by brainstem trauma
Locked-in Syndrome
•Condition in which a patient is aware and awake but cannot move or communicate verbally because of complete paralysis of nearly all voluntary muscles except the eyes
Due to brainstem damage
Quadriplegia
Paralysis and loss of sensation in the legs and arms due to spinal cord injury
Paraplegia
Paralysis and loss of sensation confined to legs and lower body due to spinal cord injury
A movement module preprogrammed by the brain and produced as a unit is called a _____.
motor sequence
The _____ organize(s) movement sequences.
premotor cortex
Fritsch and Hitzig
Discovered they could electrically stimulate the neocortex of an anesthetized dog to produce movements of the mouth, limbs, and paws on the opposite side of the dog’s body
Wilder Penfield
Confirmed the role of the primary motor cortex in producing movement in humans
Homunculus
Representation of the human body in the sensory or motor cortex
Topographic organization
Neural spatial representation of the body or areas of the sensory world perceived by a sensory organ
The parts of the motor cortex that control the ______________ are disproportionately larger than parts of the motor cortex that control other areas
hands, fingers, lips, and tongue
Motor cortex represents not muscles but rather__________.
movement categories
Constraint-induced Therapy
forces use of the affected limb as a major therapy for stroke-induced limb paralysis
Effectiveness depends on frustration of the good limb, which promotes a concerted effort to use the bad limb and promotes neural plasticity.
Corticospinal tract
Bundle of nerve fibers directly connecting the cerebral cortex to the spinal cord, branching at the brainstem into an opposite-side lateral tract that informs movement of limbs and digits and a same-side anterior tract that informs movement of the trunk
Lateral corticospinal tract
•Branches at the brainstem level, crossing over to the opposite side of the brain and spinal cord
•Moves the digits and limbs on the opposite side of the body
Ventral (anterior) corticospinal tract
•Remains on the same side of the brain and spinal cord
•Moves the muscles of the midline body (trunk) on the same side of the body
Two Kinds of neurons in the spinal column’s ventral
Interneurons, connect to motor neurons, and motor neurons, that connect to muscle
Laterally located motor neurons
control the fingers and hands
Intermediately located motor neurons
control the arms and shoulders
The most medially located motor neurons______.
control the trunk
Extensor
Moves (extends) the limb away from the trunk
Flexor
Moves the limb toward the trunk
The main efferent pathways from the motor cortex to the brainstem to the spinal cord are the _____.
Corticospinal tracts
Corticospinal-tract fibers that cross to the opposite side of the spinal cord form the _____ tracts
lateral
The basal ganglia receive input from:
All areas of the neocortex and allocortex, including motor cortex
The basal ganglia project back to:
the motor cortex and substantia nigra
The basal ganglia functions include:
association or habit learning, motivation, emotion, and motor control
Nuclei forming the basal ganglia include:
•Caudate nucleus and putamen
•Subthalamic nucleus
•Globus pallidus
Damage to the basal ganglia can produce two main types of motor symptoms:
Hyperkinetic and Hypokinetic
Hyperkinetic symptom
Damage to the caudate putamen may cause unwanted writhing and twitching movements called dyskinesias; seen in Huntington disease and Tourette syndrome.
Hypokinetic symptom
Damage to the basal ganglia may result in a loss of motor ability, leading to rigidity and difficulty initiating and producing movement; seen in Parkinson disease.
Volume control theory
The globus pallidus internal acts like a volume control on the motor cortex.
If it is turned up, movement is blocked; if it is turned down, movement is allowed.
Referred Pain
Pain that arises in one of the internal organs but is felt on the surface of the body. Ex. heart attack=upper arm pain
Anatomy of the cerebellum
Flocculus
Two hemispheres
Homuncular organization
Lateral parts
Medial parts
Lateral parts (Cerebral hemispheres)
Controls movement of limbs, hands, feet, and digits
Medial Parts (Cerebral hemispheres)
Control movement of face and midline of body
Cerebellum has information about both versions of the movement —_______—and can calculate the error and tell the cortex how to correct the movement.
what you intended to do and what you actually did
The _____ contribute(s) to motor control by adjusting the force associated with each movement.
basal ganglia
The cerebellum contributes to motor control by improving movement _____.
timing
Somatosensory system
•Tells us what the body is up to and what’s going on in the environment by providing bodily sensations such as touch, temperature, pain, position in space, and movement of the joints
•Allows us to distinguish between what the world does to us and what we do to it
Glabrous skin
Skin that does not have hair follicles but contains larger numbers of sensory receptors than do other skin areas.
Nociception(Somatosensory Receptors)
•Perception of pain, temperature, and itch
•Free nerve endings activated by chemicals
Hapsis (Somatosensory Receptors)
•Perceive fine touch and pressure and identify objects that we touch and grasp
•Activated by mechanical stimulation of the hair, tissue, or capsule
Proprioception (Somatosensory Receptors)
•Perception of the location and movement of the body
•Sensitive to the stretch of muscles and tendons and the movement of joints
Rapidly adapting receptor
responds briefly to the beginning and end of a stimulus on the body
Haptic receptors that respond to touch (Meissner corpuscles), to fluttering sensations (Pacinian corpuscles), and to vibration (Ruffini corpuscles).
Slowly adapting receptor
Body sensory receptor that responds as long as a sensory stimulus is on the body
Nociceptive receptors that respond to sharp and dull pain and those that respond to heat/ cold; Merkel’s receptors (steady skin indentation) and hair receptors (flutter or steady skin indentation)
Proprioceptive and haptic neurons (Posterior Root Ganglion Neurons)
•Carry information about location and movement (proprioception) and about touch and pressure (hapsis)
•Large, well-myelinated axons (fast)
Nocioceptive neurons
•Pain, temperature, and itch information
•Small axons with little or no myelination (slow)
Deafferentation
Loss of incoming sensory input usually due to damage to sensory fibers; also loss of any afferent input to a structure
Ipsilateral
Using/on the same side of your body
Contralateral
Using/on opposite sides of your body, e.g. your right arm and your left leg.
The haptic and proprioceptive axons for touch and body awareness ascend the spinal cord_________.
ipsilaterally
Nociceptive (pain, temperature, itch) nerve fibers synapse with neurons whose axons cross to the_________.
contralateral side
The Posterior Spinothalamic Tract
carries haptic and proprioceptive information via fine-touch and pressure fibers
The Anterior Spinothalamic Tract
Pathway from the spinal cord to the thalamus that carries information about pain and temperature toward the brain.
Monosynaptic reflex
reflex requiring one synapse between sensory input and movement
The ______________ is the main pain pathway to the brain.
anterior spinothalamic tract
Reticular formation pathway
associated with arousal
Amygdala pathway:
associated with emotional responses
Hypothalamus pathway:
Associated with hormonal and cardiovascular responses
Gate theory of pain
A spinal cord interneuron receives excitatory input (plus signs) from the fine-touch and pressure pathway; and inhibitory input (minus signs) from the pain and temperature pathway. The interneuron’s relative activity then determines whether pain and temperature information ascends to the brain.
Within an ear, a vestibular organ contains:
•Three semicircular canals
•Otolith organs (utricle and saccule)
Vestibular organs have two functions:
•Tell the position of the body in relation to gravity
•Signal changes in the direction and speed of head movements
Vestibular System and Balance
When the head moves, fluid (endolymph) located within the semicircular canals pushes against hair cells, which causes bending of the cilia located on top of the hair cells
Vertigo
•From the Latin for “spinning”
•Sensation of spinning when one is not moving
•Dysfunction of the inner ear
Ménière disease
Disorder of the inner ear resulting in vertigo and loss of balance
_____ is the perception of pain, temperature, or itch.
Nociception
The part of the thalamus that carries information about body senses to the somatosensory cortex is called the _____.
ventrolateral spinothalamic tract
Primary somatosensory cortex
•Receives projections from the thalamus
•Brodmann’s areas 3–1–2
•Begins the process of constructing perceptions from somatosensory information
Secondary somatosensory cortex
•Located behind the primary somatosensory cortex
•Brodmann’s areas 5 and 7
•Refines the construction of perceptions, projects to the frontal cortex
Apraxia
Inability to make voluntary movements in the absence of paralysis or other motor or sensory impairment, especially an inability to make proper use of an obect.
The somatosensory cortex plays an important role in_______.
confirming that movements have taken place.
Damage to the secondary somatosensory cortex (SII) produces _____, an inability to complete a series of movements.
apraxia
Hapsis
Perceptual ability to discriminate obects on the basis of touch
Meniere Disease
Disorder of the middle ear resulting in vertigo and loss of balance.
Neuroprosthetics
Field that develops computer-assisted devices to replace lost biological function
Pain gate
Hypothetical neural circuit in which activity in fine-touch and pressure pathways diminishes the activity in pain and temperature pathways
Periaqueductal gray matter (PAG)
Nuclei in the midbrain that surround the cerebral aqueduct oining the third and fourth ventricles; neurons contain circuits for species typical behaviors (e.g., female sexual behavior) and play an important role in the modulation of pain
Position-point Theory
Idea that the motor cortex allows an appropriate body part to be moved to a point in space
Proprioception
Perception of the position and movement of the body, limbs, and head