GN 301 Extra Credit 2

An alteration in the DNA from an AT base pair to a CG base pair is called a ___.

transversion (purine > pyramidine)

A change in the DNA from a GC base pair to a CG base pair is called a ___ mutation.

Point

An alteration in the DNA from an CG base pair to a TA base pair is called a ___.

Transition (pyrimidine > pyramidine)

The coding strand of a normal and a mutant DNA sequence are shown below:

Normal:  5’ – C A A A T G A C T A A T G G C T G A C A G C A T A A – 3’

Mutant: 5’ – C A A A T G A C T A A A T G G C T G A C A G C A T A A – 3’

The mutation can be described as a

frameshift

The mutation can be described as a(n)

insertion

At the protein level, this mutation can best be described as a

Readthrough

Two parents have a trait. Their daughter does not have the trait, but their son does have the trait. Draw the pedigree on scratch paper and shade in those individuals who have the trait. 

Which mode(s) of inheritance are consistent with the inheritance pattern of the shaded trait? Select all that apply.

(0.75 points out of 1.5) \n X-Linked Dominant

\
Autosomal Dominant

Two parents have a trait. Their son does not have the trait, but their daughter does have the trait. Draw the pedigree on scratch paper and shade in those individuals who have the trait. 

Which mode(s) of inheritance are consistent with the inheritance pattern of the shaded trait? Select all that apply.

Select one or more:

\n X-Linked Dominant

and

Autosomal Dominant

Refer to the following cross for these questions:

Aa bb Cc Dd Ee   x   Aa BB cc DD EY

How many different gametes can be formed form the individual of genotype AaBBccDDEY? Give your answer as a number

4 (Aa, EY)

How many different genotypes are expected among the progeny of this cross? Give your answer as a number

48

(3 x 1 x 2 x 2 x 4)

(AA Aa aa x Bb x Cc cc x DD Dd x EE EY Ee Ye)

What is the probability that the first child from this cross will be a son that shows all of the dominant characteristics?

3/32

Select all of the individuals who are expected to be female based on chromosome composition.

Select one or more:

XO and XXX (nothing with Y)

What is the sex chromosome composition of an individual who has guevedoces?

XY

Marfan Syndrome shows ______ because individuals with this disorder have a variety of abnormalities including long limbs, weak connective tissue, and abnormal heart valves.

pleiotropy

Huntington's Disease often shows ____ since the disorder tends to present earlier and progress more rapidly in later generations.

anticipation

Select all  couples that could be parents for a child that has the blood type M, B-.

\
Select one or more:

Father of type MN, B+ and Mother of type M, AB+

Father of type MN, AB+ and Mother of type M, O-

Father of type M, B- and Mother of type MN, A+

An individual has the chromosomes shown below. Which gamete will be produced the least frequently by this individual?

QrT