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Last updated 2:55 PM on 4/1/26
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12 Terms

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Cranial

face + cranial ganglia

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Vagal

enteric nervous system (MAJOR contributor)

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Trunk

DRG, sympathetic ganglia, adrenal medulla, melanocytes

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Sacral

enteric nervous system (MINOR, distal gut)

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Two migration patterns

cranial migration and trunk migration.

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Dorsal root ganglia (DRG Neurons)

  • Cell bodies are outside spinal cord

  • One process splits into:

    • Afferent → to body (sensory)

    • Efferent → into spinal cord

👉 keyword: bifurcates

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. Sensory Neuron Types

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Small + thin/unmyelinated → SLOW

  • Nociceptors, Thermoreceptors

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large + myelinated → FAST

Mechanoreceptors, Proprioceptors

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Specific Mechanoreceptors

  • Meissner’s → light touch

  • Pacinian → deep pressure + vibration

  • Ruffini → stretch

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Nociceptor subtypes

peptidergic (respond to NGF)

non-peptidergic (respond to GDNF)

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Two waves of DRG neurogenesis

1. First wave: large-diameter neurons (proprioceptors, mechanoreceptors)

2. Second wave: small-diameter neurons (thermoreceptors, nociceptors)