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Transformation
Change in genotype and phenotype due to assimilation of foreign DNA.
Bacteriophages (phages)
Viruses that infect bacteria.
Virus
DNA or RNA enclosed by a protective coat, often simply protein.
Double helix
The pattern of DNA; two strands intertwined in a ladder-like structure.
Antiparallel
their subunits run in opposite directions
DNA replication
The copying of DNA.
Semiconservative model of replication
when a double helix replicates, each daughter molecule will have one old strand and one new strand
Origins of replication
where replication begins.
Replication fork
The Y-shaped region where parental DNA strands are being unwound.
Helicases
Enzymes that untwist the double helix at the replication forks.
Single-strand binding proteins
bind to stabilize the unwinding DNA
Topoisomerase
relieves the strain of twisting the double helix by breakingswiveling and rejoining DNA strands
Primer
the piece of RNA that makes the initial nucleotide chain
Primase
synthesizes the RNA primer.
DNA Polymerase III
catalyzes the synthesis of new DNA at a replication fork.
DNA polymerase I
fixes DNA.
Leading strand
the DNA strand that is made continuously
Lagging strand
the second strand of DNA replicated 5’-3’ but in fragments
Okazaki fragments
Segments made on the lagging strand
DNA ligase
puts together the Okazaki fragments
Mismatch repair
when DNA bases don’t match, repair enzymes replace theincorrectly paired nucleotides
Nucleotide excision repair
a nuclease cuts out and replaces damagedstretches of DNA
Telomeres
the ends of DNA molecules in eukaryotes
Chromatin
DNA with proteins.
Histones
proteins that are responsible for the main level of DNA packing ininterphase chromatin
Nucleosome
compound of DNA wound twice around a core of eighthistones, two each of the four main histone types
Euchromatin
Loosely packed form of chromatin.
Heterochromatin
densely packed DNA (centromeres and telomeres)