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Kills pancreatic beta cells
Streptozotcin (STZ)
Insulin producing cells in the pancreas—endocrine cells
Beta cells
90% of diabetes, insulin resistance, can be reversed, often due to lifestyle
Type 2 diabetes
Autoimmune disorder, lack of insulin, reverseable
type 1 diabetes
Main duck used in the poultry industry; developers=young breeders, meat=grow out; 1:5 ratio
Pekin duck
Curtain sided, natural light and ventilattion,18-24hrs of light, 1:1.2 feed ratio, MKW 28-45 days
Duck barn
Main chicken breeds in layer industry
White leghorn crosses, brown hyline
Animals that can't regulate their body heat
Poikilotherms
Homeostasis- Hypothalamus
Maintaining a dynamic constancy of internal environment
Within an organ being regulated (ex. body temp)
Intrinsic
Outside of organ being regulated (ex. hormones)
Extrinsic
Sensor, Integrating center, effector
detects change, determines response, produces result
Amplifies change, until
Positive feedback loop
Doesn’t amplify change, constant
Negative feedback loop
Reseting of physiological zero for dynamic stability and regulated change
Rheostasis
Biological bases for behavior
Brain
Basic functional unit of nervous system; can’t divide by mitosis; respond to physical and chemical stimuli; electrochemical impulses & chemical regulators
Neurons

Sensory neurons, like on the skin
Pseudounipolar neurons

Have two processes, in the retina
Bipolar neurons

Several dendrites and one axon; motor neurons; majority of neurons
Multipolar neurons
Junction between 2 neurons; electrical (gap junctions), and chemical (chemical messanger)
Synapse
One cell influences many cells
Divergence
Many cells influence one cell
Convergence
Pons and spinal cord (autonomic functions like heart rate, respiratory rate, ect.), and cerebellum (fine motor movement and memory (don’t think, just do))
Rhombencephalon or hind brain
Behavior, serotonin, dopamine
Mesencephalon or midbrain
Contains diencephalon which includes the hypothalamus and thalamus
Prosencephalon or forebrain)
basal nuclei, cerebral cortex, thinky thinky bits
Telencephalon or cerebrum
~800 in mammals, all other hormones and neurotransmitters influence it
GnRH
Another outlet for physiological control of homeostasis
Behavior
PFL&NFL adapt to pressures by actively changing internal parameters
Allostasis
Anxiety disorders, stress; best receptive to change = survivors, fight or flight, stress response
Alus Cornelius, Darwin, Walter Cannon, Seyle
Predator/prey, startle, predator V predator, waling in a barn; neurogenic response (fight/flight); part of autonomic nervous system
Seyle phase one- Alarm
Head and low spinal cord; rest/digest
Parasympathetic
Mid spinal cord; fight/flight; increases blood glucose via glycolysis and gluconeogenesis
sympathetic
Makes epinephrine —> norepinephrine —> dopamine
Tyrosine
Make serotonin —> melatonin
Tryptophan
Physiological response to prolonged stressor; the humoral response; hypothalamatic, pituitary, adrenal response
Seyle Phase 2- resistance
bird hypo, pit, adrenal response, increase blood glucose
CRH, ACTH ,Glucocorticoid
Corticosterone, primary role in energy and metabolism (control blood glucose levels), Decrease insulin sensitivity (except brain), good in short term bad in long term
Glucocorticoids
Can’t physically cope with stressor; get sick or DIE
Seyle phase 3- exhaustion
behavior, glucocorticoids, HLR; corticosterone inhibits growth hormone RH
How to measure stress
Harm others vs harm themselves
Plucking vs Picking
Pre-encounter threat: prior to encounter, sympathetic dominant
Post-encounter threat: freeze, cognitive behavior, parasympathetic dominant
Circa threat: fight or flight
Fear freeze
ARAS; orient to threat; turn off to go to sleep; brain inhibits movement
Ascending reticular attention system
LC- main neural pathway associated with freeze
Locus coeruleus
What does cervical dislocation do
destroy pons
group of neurons with similar functions
nucleus
forebrain nuclei form ring around brain stem for basic emotional drives
Limbic system
connects limbic system; Fornix the biggest one
Papez Circuit
Feeding-:Hypothalamus, AgRP= strongest hunger signal
Sex: opposite of feeding; Insulin & Leptin = repro
Fear and Aggression
3 basic behaviors
Dura mater, arachnoid mater, pia mater; wrap, nourish, protect brain
Meninges
What does the brain want constantly?
Glucose and oxygen
causes limp birds; breaks down acetylcholine; caused by weed killer
Acetylcholinesterase
Initiate skeletal muscle movement by Substantia Nigra; can prevent Parkinson’s; mesolimbic dopamine system; derived from tyrosine
Dopamine
Serotonin and melatonin; derived from tryptophan; regulation of mood, behavior, appetite; affective state in birds
Inolamines
Long lasting mental state influencing emotions
Affective state
How many duck tongues in a pound?
87
Higher activity of serotonin and dopamine vs lower activity of serotonin and dopamine
Decrease vs Increase turnover
Secretes melatonin; circadian rhythms, light-dark changes
Pineall gland
Modified amino acids: glutamic acid is the strongest
Neurotransmitters
Makes morphine-like compounds to regulate pain
Endogenous opioids
inhibits reproduction: memory and learning; synthesized from L-argenine
Neuropeptide
98% fat free, 6-8ft fence, mature in 18 months, short day breeders, 1:1 ratio, 56 day incubation, 50-70% hatch rate, no egg tooth, splayed legs, need laying hen diet
Emus
Stuff we control, muscles, relays to ANS
Peripheral nervous system
protective mechanism triggered by nociceptors, storage of experiences in memory, substance P propagates it, analgesia suppresses it
Pain
rods and cones, oil droplets, wave particle duality, wavelength specific, quanta activated
Photoreceptors
How many cones do birds have
4, 5 counting double cone
turns blue light into red, activation requires thyroid access, red and white can maintain reproduction
Deep brain photoreceptors
day vs night
photophase vs scotophase
Seet, mobbing, distress
Vocalizations
How many noises does a duck make
19 distinct quacks and 3 egg laying quacks
How many quacks do drakes make
4 quacks
Sounds are based on
Social structure, items in environment