Substance Abuse (Chapter 17)

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Last updated 6:20 PM on 4/12/26
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4 Terms

1
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Acamprosate (campral)

Action:

  • NMDA receptor antagonist

Uses:

  • Chronic alcoholism; with other therapies, enhances abstinence and reduces drinking rates

2
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Acamprosate (campral) Adverse effects

COMMON:

  • Diarrhea

SERIOUS:

  • Suicidal actions

  • CONTRAINDICATED in patients with severe renal failure

3
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Disulfiram (antabuse)

Action:

  • When alcohol is ingested, it produces nausea, severe vomiting, sweating, throbbing, dizziness, blurred vision

Uses:

  • Chronic alcoholism, with other therapies

4
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Disulfiram (antabuse) Adverse Effects

COMMON:

  • Drowsiness, fatigue, headache, impotence, metallic taste

SERIOUS:

  • Hepatotoxicity, hypersensitivity

  • DO NOT administer to acutely intoxicated patient; no contact with ethol