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Rogers and kesner (2003) outline + evaluation (for animal model essay)
aim: test the role of acetylcholine on the formation of spatial memory
procedure:
30 rats were put in a maze woith food in a corner and became familiar with it / no longer scared of the environmennt)
injected directly in the hippocampus with either: (randomly allocated)
scopolamine (antagonist for acetylcholine receptors)
saline solution
so that injection did not cause a variable in memory
tested the errors made by the rats in the first 5 trials to find the food in the corner of the maze
Findings:
participants in the experimental conditions took longfer to find food/ higher erros made=> suggests that acetylcholine may play a role in the formation of spatial memory
Strenghts:
Highly standardize => replicable / reliable
high internal validity=> lots of control (es. placebo) / true experiment
cause and effect relationship established
can help treatments of dementia / alzheimer
Limitations:
reductionsit approach
confounding variable of injection (may have increased adrenaline)
difference between how acetylcholine works in humans rats
human brain is more complex than rats
antonova et al (2011) outline + evaluation
Aim:
test the hippocampus activity in the brain after scopolamine injection (to test role of acetylcholine in the formation of spatial memory)
Procedure:
20 helathy male adults
conducted complex virtuality game in an fMRI
randomly allocated in these two condition:
injected with scopolamine
injected with scopolamine solution
double blind
counter balanced
participants were in an arena and had to became familiar with the environment, than they had to reach a pole. after screeen would go blank for 30 seconds and put in a diffrent initial place, and had to find the pole again.
for 6 trials
Findings:
significantly lower activity in the brain of participants in the experimental condition. Took slightly longer/ made more mistakes. Thus acetylcholine play a role in the brain and thus in the formation of memory.
Strenghts:
Highly controlled (standardized procedure/ double blind (no research bias)/ counter balanced ( no practise effect)
Limitations:
small sample size (low population validity)
participants felt stress due to injection=> externous variable
limitations of using animal models (brain and behaviour essay)
brain more complex in humans than in rats
acetylcholine may play a different role in rats than in humans (assumption of the contrary in teh experiments)
reductionsit approach
can we generalize from rats to humans
drugs that works in rat do not work in humans.
cases et al (1995) outline + evaluation
Aim:
study the genetic origins of depression
Procedure:
transgenic mouse used
gene that produces MAOA (enzyme that breaks down serotonin and adrenaline) was removed in rats
Findings:
male offsprings without that gene were more aggressive
high levels of serotonin/ adrenaline in all the offsprings
strenghts:
cause and effect relationship was established
standardize procedure
limitations:
can explain human behaviour.
reductionist
low ecological validity as it was done in a lab
Caspi et al (2002) outline + evaluation
Aim:
test if the MAOA gene had an effect on aggressive behaviour
Procedure:
26 years old longitudinal study
1000 kids from new zealand
genotype of the boys were studies
36% of the boys were maltreated ( either rejected by their mother/ physically / sexually abuused)
Findings:
if the boy had MAOA gene and maltreated => higher chance to bully when was younger / criminal / antisocial behaviour)
if the boy did NOT have MAOA gene and maltreated=> did not develop this behaviour.
strenghts:
longitudinal study
big sample size
limitations:
correlational in nature ( no cause and effect relationship)
reductionist
winslow outline + evaluation
aim: test role of vasopressin in rats in the likelyhood of developing of monogamous relationship
procedure:
rats injected with either:
saline solution
antagonist for vasopressin solution
rats put in a cage with a femal in heat
after mating, put in a cage with three rooms:
one with the previous sexual partener
one with another female
findings:
rats injected with antagonist spend equal time with their previous mate and the other female
rats injected with the placebo conditions stayed only with their sexiual partner
strenghts:
high controlled true experiments => high ecological validity
can we extend the findings to human?=> than yap about Walum study
Walum outline + evaluation
aim: test if the level of vasopressin would predict the level of marital satisfatcion
procedure:
500 mens