coagulation cascade

1. Coagulation factors are labeled by:
A. Letters
B. Numbers
C. Roman numerals
D. Symbols

c

Active factor form is indicated by:
A. “+”
B. “a”
C. “*”
D. “x”

b

Extrinsic pathway involves:
A. XII
B. VII
C. IX
D. XI

b

Intrinsic pathway begins with:
A. VII
B. X
C. XII
D. II

c

Common pathway starts at:
A. VIII
B. IX
C. X
D. XI

c

Thrombin converts:
A. RBC → WBC
B. Fibrin → fibrinogen
C. Fibrinogen → fibrin
D. Platelets → clot

c

PT evaluates:
A. Intrinsic
B. Extrinsic + common
C. Platelets
D. RBC

b

aPTT evaluates:
A. Extrinsic
B. Intrinsic + common
C. Platelets
D. RBC

b

Vitamin K–dependent factors include:
A. I, V, VIII
B. II, VII, IX, X
C. XI, bXII
D. XIII only

b

D-dimer indicates:
A. RBC destruction
B. Platelet count
C. Clot breakdown
D. Infection

c

list the intrinsic pathway factors

xii xi ix viii

list the extrinsic pathway factors

vii iii

what is the role of thrombin

converts fibrinogen to fibrin, activates clotting

what does mixing study determine

factor deficiency v inhibitor

name 2 natural anticoagulants

antithrombin, protein c, protein s