The TCA cycle

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Last updated 2:40 PM on 5/1/26
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20 Terms

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citrate synthase

oxaloacetate (+ acetyl-CoA) -> Citrate

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aconitase

citrate -> cis-aconitate

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aconitase (2nd step)

cis-aconitate -> isocitrate

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isocitrate dehydrogenase

isocitrate -> alpha-ketoglutarate (+ NADH)

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alpha-ketoglutarate dehydrogenase complex

alpha-ketoglutarate -> succinyl-CoA (+ NADH)

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succinyl-CoA synthetase

succinate-CoA -> succinate (+ GTP)

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succinate dehydrogenase

succinate -> fumarate (+ FADH2)

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fumarase

fumarate -> malate

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malate dehydrogenase

malate -> oxalacetate (+ NADH)

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every FADH2 molecule yields

1.5 ATP

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every NADH molecule yields

2.5 ATP

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every acetyl-CoA molecule yields

10 ATP

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oxidation -> FADH2

1st step of beta-oxidation

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hydration

2nd step of beta-oxidation

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thiolation

4th step of beta-oxidation

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oxidation -> NADH

3rd step of beta-oxidation

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1st enzyme of beta oxidation

acyl-CoA dehydrogenase

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2nd enzyme of beta oxidation

enol-CoA hydratase

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3rd enzyme of beta oxidation

beta-hydroxy acyl-CoA dehydrogenase

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4th enzyme of beta oxidation

thiolase