Mnemonics

Drugs/Conditions that can cause hypothyroidism

I TALC

I: interferons*

T: tyrosine kinase inhibitors (sutinib)

A: amiodarone*

L: lithium

C: cbz

• conditions: hashimoto’s disease, iodine deficiency

*can also cause hyperthyroidism

levothyroxine IV:PO

0.75:1

levothyroxine tablet colors

Orangutans Will Vomit On You Right Before They Become Large, Proud Giants

25 orange

50 white (no dye)

75 violet

88 olive

100 yellow

112 rose

125 brown

137 turqouise

150 blue

175 lilac

200 pink

300 green

preferred antithyroid med in 1st trimester?

PTU

• MMI can be used in 2nd/3rd

preferred antithyroid med DOC

MMI

DOC during thyroid storm

PTU + SSKI or Lugol’s solution

• BB + steroid (dexamethasone) + aggressive cooling

Systemic Steroids (PO, IV) Dose Equivalence

Cows Hate Pretty People, Mostly They Drink Beer

Cortisone 25

hydrocortisone 20

prednisone 5

prednisolone 5

methylprednisolone 4

triamcinolone 4

dexamethasone 0.75

betamethasone 0.6

when is someone immunocompromised from steroids?

≥2mg/kg/d or ≥20mg/d of prednisone or prednisolone equivalence for ≥2 weeks

medrol dose pack contains how many tabs?

21 × 4mg tabs

6 day 1

5 day 2

4 day 3

3 day 4

2 day 5

1 day 6

anti-tnf biological DMARDs

1. etanercept (Enbrel) SC weekly

2. adalimumab (Humira) SC every other week

3. infliximab (Remicade) IV (NS only), filter required

4. certolizumab pegol (Cimzia) SC every other week

5. golimumab (Simponi)

required screenings for biologics

methotrexate: chest xray, HBV, HCV

etancercept (or other anti-TNF): screen for TB and HBV

JAK inhibitors: can cause TB

rituximab: screen for HBV and HCV

tocilizumab: screen for TB

S1P: screen for VZV antibodies

drugs that cause DILE

My Poor Mom Makes Pretty Hot Tacos In Queens

methimazole

PTU

methyldopa

minocycline

procainamide

hydralazine

terbinafine

isoniazid

quinidine

anti-tnf drugs (biologics)

SLE treatment

nondrug: sunscreens and sun protections

mild: hydroxychloroquine alone

moderate/severe: cyclophosphamide, azathioprine, mycophenolate mofetil, cyclosporine, belimumab

multiple sclerosis treatment

1. interferon beta formulations

2. glatiramer acetate

relapsing remitting MS: oral DMTs fingolimod, diroximel fumarate, ozanimod

preferred DOC for MS and pregnancy

glatiramer acetate

SC daily or SC 3x/week

interferon beta products

1a: avonex IM weekly or SC 3x/week

1b: SC every other day

pegylated 1a: SC every 14 days

psychiatric disorders, inc LFTs, thyroid dysfunction, injection site necrosis, flu-like sx

which S1P requires genotyping?

siponimod: CYP2C9×3/*3 genotype required

alemtuzumab MOA

CD52 directed cytolytic monoclonal antibody

REMS required

which drug causes progressive multifocal leukoencephalopathy (PML)?

natalizumab (Tysarbi)

REMS required

every 4 weeks

what drug is used for prevention of Raynaud’s phenomenon

CCB nifedipine

Drug-Induced Raynaud’s

beta blockers

bleomycin/cisplatin

sympathomimetics

MG treatment

pyridostigmine (Mestinon)

• cholinergic effects: excess ACh (salivation, lacrimation, urination, diarrhea)

what PDE4 inhibitor is used in psoriasis

apremilast (Otezla)

weight loss, diarrhea

Enbrel’s warnings

hepatotoxic

malignancy

exacerbation of HF

risk of infection

Copaxone

Glatiramer acetate

SE: sweating and dyspnea, chest pain, rash

use: MS

admin: SC daily or 3x/week, preferred during pregnancy

select drugs that can cause hemolytic anemia

immune-mediated (+coombs test)

• penicillins

• cephalosporins

• isoniazid

• levodopa

• methyldopa

• rifampin

G6PD deficiency

• dapsone

• mehylene bl;ue

• nitrofurantoin

• pegloticase

• rasburicase

• primaquine

Both: quinidine, quinine, sulfonamides

Statin DDIs

G-PACMAN

G-PACMAN

G: grapefruit juice

P: protease inhibitors (ritonavir)

A: azoles

C: cyclosporin, cobicistat

M: macrolides (except azithromycin)

A: amiodarone (dronedarone)

N: non-DHP CCBs

H. pyloric treatment (Please Take My Bacteria)

PPI BID

tetracycline 500mg QID

metronidazole 500mg TID-QID

bismuth 300mg QID

x 14 days

medds to protect from light

protect every nec med from daylight

phytonadione (vitamin K)

epoprostenol

nitroprusside

micafungin

doxycycline

CYP3A4 inducers

please call peter really soon

phenytoin

carbamazepine

phenobarbital

rifampin

st. johns wort, smoking

meds you shouldn’t refrigerate

dear pharmacists, freezing meds might break

dexmedetomidine (concentrated)

phenytoin

furosemide

metronidazole

moxifloxacin

bactrim

enoxaparin

drugs with photosensitivity

too much sun turns skin very red and freaking disgusting

tetracyclines

methotrexate

sulfa drugs

tacrolimus

st. johns wort

voriconazole

retinoids

amiodarone

fluoroquinolones

diuretics (thiazides/loops)

meds requiring an acidic gut (6)

a lady ran in crack acid

azoles

ledipsavir

risendronate DR

iron

cephalosporins

anti-retrovirals (NNRI, PI)

meningitis treatment (CAD)

ceftriaxone everyone

ampicillin: add for age, pregnancy, immuno (listeria coverage)

dexamethasone before or with 1st dose

neonates: amp + gent/ceftazadime/cefepime

1-50: ceftriaxone + vancomycin

DILE

my pretty mom made pie, her aunt tried it quickly

MMI

PTU

methyldopa

minocycline

procainamide

hydralazine

anti-TNF

terbinafine

isonazid

quinidine

steroid conversions

cute happy pharmacists prefer mixing the drugs before

cortisone 25

hydrocortisone 20

prednisone 5

prednisolone 5

methylprednisolone 4

triamcinolone 4

dexamethasone 0.75

betamethasone 0.6

warfarin colors

please let greg brown bring peaches to your wedding

pink 1

lavendar 2

green 2.5

brown 3

blue 4

peach 5

teal 6

yellow 7.5

white 10

drus that increase Uric Acid

(uric acid) can always deposit nasty painful crystals

cyclosporine

aspirin

diuretics (loops/thiazides)

niacin

pyrazinamide

chemo (TLS)

statin equivalence

pharmacists rock at saving lives preventing fat

pitavastatin 2

rosuvastatin 5

atorvastatin 10

simvastatin 20

lovastatin 40

pravastatin 40

fluvastatin 80

drugs causing seizures

my big back freaking loves crunchy tacos tequilla margs

meperidine

bupropion

beta lactams

FQ

lithium

clozapine

TCAs

tramadol

mefloquine

drugs that require non-PVC containers

leach absorbs to take in nutrients

lorazepam

amiodarone

tacrolimus

taxanes (except paclitaxel-albumin

drugs that mix in DEXTROSE only

only sugar always

oxaliplatin

sulfa/tmp

amphotericin

drugs to mix in SALINE only

A DIAbetic Can’t Eat Pie

ampicillin

daptomycin

infliximab

ampicillin/sulbactam

caspofungin (Cancidas)

ertapenem (Invanz)

phenytoin (Dilantin)

drugs with filter requirements

my GAL Is PAT who has a MaP

golimumab

amphotericin b (lipid)

lipids (1.2 micron)

isavuconazium

phenytoin (IV only, not iv push)

amiodarone

taxanes (cabazitaxel, paclitaxel)

mannitol >20%

parenteral nutrition 1.2 micron