OPI Questions lmao

Which of the following opportunistic infections require a delay in starting antiretroviral

therapy of at least 2 weeks from the start of treatment?

Cryptococcal meningitis

In which scenario would an HIV+ patient be started on Mycobacterium avium complex

primary prophylaxis, assuming their CD4+ is < 50 cells/mm

The patient cannot start antiretroviral therapy

Which of the following agent(s) is appropriate for prophylaxis against Pneumocystis

jirovecii pneumonia AND Toxoplasmosis?

Trimethoprim-sulfamethoxazole

HT is a 62-year-old HIV+ female who presents to the hospital with new onset confusion,

fevers, neck pain, and headaches. Her CD4+ count at the time of admission is 17

cells/mm3. A spinal tap with CSF cultures and cell counts is completed, showing elevated

WBC with a lymphocytic predominance, normal glucose, slight elevations in proteins,

and a high opening pressure. Cultures are currently pending, however Cryptococcal

antigen testing on the CSF sample is positive. What would be the most appropriate

treatment to start at this time

Liposomal amphotericin B + flucytosine

DB is a 36-year-old male who was recently diagnosed with HIV and started on ART about

1 week ago. At that time his CD4+ count was 93 cells/mm3. He returns to the physician's

office complaining of throat pain and "gross tan patches" in his mouth. The physician

informs you that these patches are easily scraped off, and it appears the infection

extends into his throat. He has no known recent antimicrobial exposure. What would be

the most appropriate therapy to start at this time? (Drug(s) name(s) ONLY

Fluconazole