Integumentary System - Skin Anatomy and Functions (VOCABULARY)

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Vocabulary-style flashcards covering skin anatomy, layers, cells, glands, hair, nails, sensory receptors, and functions.

Last updated 2:21 AM on 9/10/25
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43 Terms

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Epidermis

The outer, visible skin layer made of stratified squamous epithelial tissue; avascular and constantly renewing; contains keratinocytes and melanocytes.

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Dermis

The middle skin layer beneath the epidermis; contains blood vessels, nerve endings, hair follicles, sweat and oil glands; has papillary and reticular sublayers.

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Hypodermis (Subcutis)

The bottom skin layer composed mostly of adipose tissue; insulates, stores energy, cushions, and anchors the skin.

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Stratum corneum

Outermost epidermal layer of dead keratinocytes; provides a protective barrier; thick skin has 20–30 layers.

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Stratum lucidum

A clear layer of flat, dead keratinocytes found only in thick skin (palms and soles).

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Stratum granulosum

Granular epidermal layer with living keratinocytes forming keratin; cells become flatter as they move toward the surface.

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Stratum spinosum

Prickle cell layer just above basale; cells appear spiny when dehydrated and interconnect via filaments.

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Stratum basale

Deepest epidermal layer; single layer of actively dividing cells that generate new epidermal cells and connect to the dermis.

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Keratinocytes

Primary epidermal cells that produce keratin; originate in the basale layer and migrate outward, eventually dying at the surface.

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Melanocytes

Pigment-producing cells in the epidermis that synthesize melanin, contributing to skin color and UV protection.

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Melanin

Pigment ranging from reddish yellow to brownish black; shields skin from UV radiation; distribution and extent affect color.

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Langerhans cells (dendritic cells)

Immune cells in the epidermis that originate in bone marrow and help defend against invaders.

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Merkel cells (tactile cells)

Tactile receptors located at the epidermis-dermis boundary; work with nerve endings to sense touch.

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Thick skin

Skin on palms and soles with five epidermal layers, including the stratum lucidum.

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Thin skin

Most of the body’s skin with four epidermal layers and lacking stratum lucidum.

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Papillary layer

Upper dermal layer of areolar connective tissue with dermal papillae that enhance grip and house capillaries.

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Dermal papillae

Projections of the papillary layer into the epidermis; create friction ridges (fingerprints) in thick skin.

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Friction ridges

Ridges formed by dermal papillae that enhance grip and leave fingerprints.

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Reticular layer

Deeper dermal layer of dense irregular connective tissue; houses nerves, vessels, and glands; forms most of the dermis.

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Dermaal blood vessels

Vascular network in the dermis that nourishes skin and regulates temperature by vasodilation and vasoconstriction.

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Hair (pili)

Keratinized strands growing from hair follicles; provides protection and sensation; growth involves keratinization in the shaft and root.

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Hair shaft

Part of the hair that extends above the skin surface; fully keratinized.

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Hair root

Part of the hair below the skin surface within the follicle; keratinization is still in progress.

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Hair cuticle

Outermost layer of hair shaft composed of overlapping keratinized cells; smooths the hair surface.

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Nails

Keratinized plates on fingers and toes; protect digits and assist in manipulation; grow from the nail root.

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Nail bed

Skin beneath the nail plate; supports nail growth and health.

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Nail root

Growth region of the nail located at the proximal end under the skin.

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Cuticle (eponychium)

Fold of skin at the base of the nail; protects the nail matrix.

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Sebaceous glands

Oil glands that secrete sebum into hair follicles to soften hair and skin and reduce water loss.

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Sebum

Oily substance produced by sebaceous glands that lubricates skin and hair.

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Sweat glands (sudoriferous glands)

Glands that produce sweat; distributed as eccrine and apocrine types contributing to temperature regulation and odor.

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Eccrine sweat glands

Most numerous sweat glands; simple coiled tubes that secrete watery sweat directly onto the skin surface for thermoregulation.

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Apocrine sweat glands

Sweat glands associated with hair follicles in axillary and anogenital regions; produce viscous, lipid-rich sweat linked to body odor.

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Vitamin D synthesis

Skin converts UV light into vitamin D; activation occurs in liver and kidneys to form calcitriol for bone health.

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UV damage to skin

Ultraviolet radiation can damage elastic fibers, suppress immunity, and increase skin cancer risk; sunscreen mitigates damage.

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Tactile receptors

Cutaneous sensory receptors in the skin that detect touch, pressure, and vibration (e.g., tactile and lamellar corpuscles).

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Tactile corpuscles

Nerve endings in the dermal papillae that provide light touch sensation.

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Lamellar corpuscles

Pressure receptors in the deeper dermis that detect sustained compression.

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Cyanosis

Bluish skin color due to low oxygen in blood; indicates poor circulation or respiratory issues.

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Jaundice

Yellowing of the skin from bilirubin buildup, usually signaling liver disorder.

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Erythema

Reddened skin from fever, inflammation, or allergy due to vascular dilation.

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Tattoo basics

Tattoos must deposit pigment into the dermis; epidermal ink removal would fade as epidermal cells shed.

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Integumentary system overview

System including skin, hair, nails, sweat glands, and sebaceous glands that protects, senses, and regulates the body.