Mechanisms

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Last updated 6:29 AM on 4/29/26
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5 Terms

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Basic (negative nucleophile)

  1. Nucleophilic attack

  2. loss of leaving group

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Acidic

  1. proton transfer to O

  2. Nucleophilic attack

  3. proton transfer to reagent

  4. proton transfer to G group

  5. loss of LG

  6. proton transfer to reagent

3
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“Base”

  1. Nucleophilic attack

  2. Loss of LG

  3. proton transfer

4
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“Base” uses

Amide, anhydride, and carboxylic acid formation

5
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Basic uses

ester formation