lo1 what is a nucleosome
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9 Terms
What is the basic building block of chromatin?
The nucleosome.
What does a nucleosome look like under an electron microscope?
It looks like "beads on a string."
What are the core histone proteins that make up a nucleosome?
Histone 2A (H2A), Histone 2B (H2B), Histone 3 (H3), and Histone 4 (H4).
What is the structure of the nucleosome core particle?
Two of each core histone (H2A, H2B, H3, H4) form an octameric nucleosome core particle.
How much DNA wraps around the nucleosome core particle?
Approximately 147bp of DNA.
What is the linker histone?
Histone 1 (H1).
Where are the N-termini of the core histones located?
They protrude from the nucleosome.
What are the protruding histone tails characterized by?
They are intrinsically disordered, making them highly flexible, and they are heavily post-translationally modifi