Oxytocin Overview

These flashcards cover the essential information regarding the pharmacology, indications, contraindications, dosing, side effects, and precautions related to the hormone Oxytocin.

Oxytocin

A hormone classified as a uterine stimulant, oxytocic, and uterotonic.

Mechanism of Action of Oxytocin

Selectively stimulates the smooth musculature of the uterus, increasing muscle tone and the frequency and strength of contractions.

Indications for Oxytocin

Used for post-partum hemorrhage and normal postpartum management after the delivery of the placenta.

Contraindications for Oxytocin

Should not be administered to patients who have had uterine or cervical surgery.

Dosage for Oxytocin IV infusion

20 - 30 Units in 1000 ml NS at 250 ml/hr, titrated to uterine response and severity of bleeding.

Optional IM dosage for Oxytocin

10 Units IM.

Side effects in the mother from Oxytocin

Hypotension, dysrhythmias, tachycardia, seizures, coma, nausea/vomiting, and potential ADH effects leading to water retention and vasoconstriction at higher doses.

Side effects in the fetus from Oxytocin

Hypoxia, asphyxia, arrhythmias, and intracranial bleeding.

Precaution when administering Oxytocin

May cause placental retention if given before delivery of the placenta.