gram (-) resistance
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15 Terms
mild CRAB infection treatment
ampicillin/sulbactam 3g q4 over 30 min
moderate-severe CRAB infection treatment
ampicillin/sulbactam 9g q8 infused over 4 hours or
27g continuous infusion
alternative CRAB infection treatment
minocycline 200mg q12
tigecycline 200mg once then 100mg q12
cefiderocol (refractory)
when to avoid tigecycline and minocycline
bloodstream and urinary tract infections
CRE (KPC) treatment
ceftazidime/avibactam
imipenem/relebactam
neropenem/vaborbactam
CRE (IMP/NDM/VIM) treatment
cefiderocol monotherapy
ceftazidime/avibactam + aztreonam
CRE (OXA-48) treatment
ceftazidime/avibactam
cefiderocol
CRE (IMP/VIM/NDM) outside urinary tract
cefiderocol
ceftazidime/avibactam
CRE (OXA-38) outside urinary tract
ceftazidime/avibactam
CRE (KPC) outside urinary tract
ceftazidime/avibactam
imipenem/relebactam
meropenem/vaborbactam
difficult to treat pseudomonas treatment uncomplicated cystitis
cefiderocol
ceftazidime/avibactam
ceftolazone/tazobactam
imipenem/relebactam
one dose of aminoglycoside
difficult to treat pseudomonas treatment complicated cystitis
cefiderocol
ceftazidime.avibactam
ceftolazone/tazobactam
imipenem/relebactam
once daily aminoglycoside
difficult to treat pseudomonas treatment outside urinary tract
ceftazidime/avibactam
ceftolazone/tazoactam
imipenem/relebactam
cefiderocol
mild stenotrophomonas treatment
cefiderocol
levofloxacin
minocycline 200mg BID
tigecycline 200m x 1 then 100mg BID
bactrim
moderate/severe stenotrophomonas treatment
ceftazidime/avibactam + aztreonam
combo therapy with 2:
cefiderocol
levofloxacin
minocycline
tigecycline
bactrim