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āAll materials, living or non-living, are composed of
Chemicals consisting of atoms.
The study of the structure/morphology of the human body and its parts; derived from Greek for āa cutting upā
Anatomy
All anatomical structures are chemicals, andā
All physiological processes are based on chemical reactions
The study of the functions of the human body and its parts; derived from Greek for ārelationship to nature.ā The structure of organs and parts of the human body determines the function.
Physiology
āSubatomic Particles
Protons, neutrons, and electrons that make up cells
āAtom
Tiny particles that make up chemicals (hydrogen, carbon)
āMolecule
Particles consisting of atoms joined together (water, glucose)
āMacromolecule
Large particles consisting of molecules (DNA, protein)
āOrganelle
Functional part of a cell (mitochondrion, lysosome)
āCell
Basic unit of structure and functions (muscle, nerve, or blood cell)
āTissue
Layer or mass of cells with specific function (adipose tissue)
āOrgan
Group of tissues with a function (heart, kidney, stomach)

āOrgan System
Group of organs with common function (digestive system)
āOrganism
Composed of organ systems interacting (human)
āNoninvasive procedures that provide images of internal structures
Ultrasound and Magnetic Resonance Scan (MR)
āUltrasound
High-frequency sound waves that provide images of soft internal structures; used to obtain sonogram of fetus in the uterus
āMagnetic Resonance Scan (MR)
Magnetic field changes alignment and spin of certain types of atoms
āMagnetic Resonance Scan (MR) provides (image)
High-resolution images of internal structures, such as the brain
Gradients and permeability
Cells move from high to low, down pressure and concentration gradients, across permeable membranes
Cellular differentiation
Specialization of cells due to gene expression
Cell membrane mechanisms
Determine entry of substances, respond to signals. Selectively permeable
Cell-to-cell communication
Via membrane receptors
Balance
Replacement of lost substances, elimination of excesses
Energy processes
Keeps cells active
āAging occurs from
The microscopic to the whole-body level
āAging- Skin wrinkles due to
Decrease in subcutaneous fat
āAging- Skin stiffens due to
Decrease in collagen and elastin
āAging- Percentage of fats in the tissues
Increases
āAging- Elevated blood glucose may progress to
Type 2 diabetes mellitus
āAging Tissues
Atrophy and organs shrink
āAging Cells reach end of ability to undergo cell division because
They lose tips of chromosomes
āAging Metabolic rate
Decreases
āAging causes decreased production of
Enzymes and other proteins. Dementia/Alzheimer disease
āAnatomical Position
Standing erect, facing forward, upper limbs at the sides, palms facing forward
āBilateral
Paired structures; on both sides
āIpsilateral
Same side (EX: Right Arm and Right Leg)
āContralateral
Opposite sides (EX: Left Leg and Right Arm)
āProximal
Close to point of attachment to trunk (Shoulder is proximal to the elbow. BUT elbow is distal to the shoulder)
āDistal
Farther from point of attachment to trunk (Elbow is distal to the shoulder. BUT shoulder is proximal to the elbow)
āSagittal section
Longitudinal cut that divides body into left and right portions
āMid-sagittal (Median) section
Divides body into equal left and right portions
āTransverse (Horizontal) section
Divides body into superior and inferior portions
āCoronal (Frontal) section
Longitudinal cut that divides body into anterior and posterior portions
ā Cross-section
A cut across the structure (burger)
āOblique section
An angular cut
āLongitudinal section
A lengthwise cut (hotdog)
āHuman body, food, and medications are all composed of
Chemicals
āAll anatomical structures are
Chemicals (physiological processes)
āMatter is anything that takes up space and has mass
Matter is composed of elements. Solids, liquids, and gases.
āChemistry concerned with composition of substances and how they change in chemical reactions
Studies composition, properties, interaction of matter
āBiochemistry
Biological chemistry, which studies physiological process and disease
Elements (92 occurring)
Simplest types of matter with certain chemical properties.
Compounds
Chemical combinations of different elements
āDifferent elements are required by the body in different amounts
Bulk elements, trace elements, and ultratrace elements
āBulk elements ("Carbon has nine oxygens per student")
CHONPS
Required by the body in large amounts (C, H, O, N, P, S)
āTrace elements
Required by the body in small amounts (Fe, I)
āUltratrace elements (Arsenic)
Required by the body in very minute amounts (As)
āTrace elements in the human body
Cobalt (Co), Copper (Cu), Fluorine (F), Iodine (I), Iron (Fe), Manganese (Mn), Zinc (Zn)
āMost abundant elements in the human body by weight
CHO
Oxygen (65.0%), Carbon (18.5%), and Hydrogen (9.5%)
āProtons
Large particlesand carries a single positive charge:
āNeutrons
Large particles and carries NO electrical charge
āElectrons
Small particles; carry a single negative charge
āAtoms are subatomic particles consisting of
A central nucleus (protons + neutrons) and electrons in constant motion around the nucleus.
āAtoms are electrically neutral because
Number of protons equals number of electrons
āAtotomic number is the element's identity, while the mass number gives the total weight of a specific atom
Number of protons in the nucleus of an atom of a specific element

āMass Number
The number of protons + neutrons in (1) atom
Electrons do not contribute to the mass of the atom because
They are so light
āMass is the amount of matter present, and weight is the heaviness due to gravitational pull on mass
Mass vs Weight

āIsotopes are atoms with
Same atomic numbers ābut different mass numbers
āAll atoms of a certain element have the same
Atomic number
āIsotopes contain
Different numbers of neutrons, but SAME number of protons & electrons
āRadioactive isotopes
Unstable, releasing energy or atomic fragments (atomic radiation) until they gain stability. Detect and treat disease
āAtomic weight
Often considered the average of the mass numbers of all of an element's isotopes
āOxygen often forms isotopes ____ with numbers representing mass numbers
O16, O17, O18
Medical uses of radioactive isotopes
Detecting coronary blood vessel disorders, evaluating kidney function, measuring hormone concentrations in body fluids, and assessing changes in bone density
Ionizing radiation
Radiation whose energy can remove electrons from atoms, resulting in the formation of ions
Examples of ionizing radiation
Alpha, beta, and gamma radiation
Free electrons can
Damage nearby atoms
Sources of ionizing radiation
X rays, naturally occurring radioactive elements in the crust of the earth, and nuclear weapons
āMolecule
Particle formed when two or more atoms chemically combine
āCompound
Particle formed when two or more atoms of different elements chemically combine
Molecular formulas
Depict the elements present and the number of each atom present in the molecule
Hā
A molecule of hydrogen
CāHāāOā
A molecule of glucose
Atomic - Number of protons in atom's nucleus
Mass- Total protons and neutrons in atom's nucleus.
Atomic Number vs. Mass Number from the periodic table
āChemical bonds.
When atoms combine with other atoms. Results of interactions between the electrons of the atoms
āElectrons occupy regions of space called Electron shells. For atoms with atomic numbers of 18 or less,
They encircle the nucleus. First shell 2 electrons, second 8 electrons, third 8 electrons.
Lower energy shells/inner orbits are filled first
And are stable with a certain number of electrons in the outermost shell (2, 8, or 18 in larger atoms).
āElectrons in the outermost shell determine
Whether an atom will react with other atoms to form chemical bonds
āIon
An electrically charged atom that gains or loses electrons to become stable
āCation
A POSTIVELY charged ion, formed when an atom LOSES electrons
āAnion
A NEGATIVE charged ion, formed when an atom GAINS electrons
āIonic Bonds
Strong chemical bonds formed when ions of opposite charge attract
āCovalent Bonds
Strong chemical bonds, formed between atoms that share electrons
āHydrogen molecules (Hā) often combine with oxygen (Oā) molecules to form
Water molecules (HāO)
Structural formulas
Show how atoms bond and are arranged in various molecules
One line between atoms means
1 pair of electrons are being shared (forming single bonds)
Synthesis, Decomposition, Exchange, and Reversible.
Types of Reactions
āNonpolar covalent bonds
Electrons are shared equally. Found in atoms with the same electronegativity
āNonpolar & Polar Covalent Bonds of the same element pull shared electrons
Equally