momba

A set of flashcards covering key terms and concepts related to drugs that target viral replication, assembly, and release.

Nucleoside analogs

Drugs that block viral replication by mimicking natural nucleotides but are chemically different, preventing successful nucleic acid production.

Acyclovir

A well-known nucleoside analog that blocks DNA replication in cells infected with specific herpes viruses.

DNA polymerase

An enzyme that synthesizes DNA molecules from nucleotides and can be inhibited by nucleoside analogs.

Guanosine

A nucleoside that acts as a building block for DNA and is mimicked by certain activated drugs like acyclovir.

Docosanol

A topical agent that blocks viral entry by inhibiting fusion, primarily used to treat cold sores caused by HHV-1.

Vapendavir

An antiviral drug in late-stage clinical trials that inhibits viral uncoating in rhinoviruses.

Endosomal environments

Cellular compartments that can be affected by chloroquine and hydroxychloroquine, potentially limiting viral penetration.

In vitro studies

Laboratory experiments conducted in a controlled environment to assess the potential effectiveness of drugs.

In vivo studies

Studies conducted within a living organism to evaluate the efficacy and safety of drugs in real biological systems.