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Why do cells require oxygen?
To synthesize ATP
What waste product is produced when cells use oxygen?
Carbon dioxide
What is the main function of the respiratory system?
To provide cells with needed oxygen and remove carbon dioxide
What are the four processes that make up respiration?
Pulmonary ventilation, pulmonary gas exchange, gas transport in blood, and tissue gas exchange
What is pulmonary ventilation?
The movement of air into and out of the lungs
What are the two phases of pulmonary ventilation?
Inspiration and expiration
What happens during inspiration?
Oxygen-rich air moves into the lungs
What happens during expiration?
Carbon dioxide rich air moves out of the lungs
What is pulmonary gas exchange?
The movement of oxygen from the air to the blood and carbon dioxide from the blood to the air
What is gas transport?
The movement of gases through the blood
What is tissue gas exchange?
The exchange of gases between blood and body tissues
What happens during tissue gas exchange?
Oxygen is delivered to tissues and carbon dioxide is picked up by the blood
What are lungs composed of?
Elastic connective tissue and tiny air sacs called alveoli
What are alveoli?
Small air sacs where gas exchange takes place
How are lungs divided structurally?
Into lobes
How many lobes does the right lung have?
Three; upper, middle, lower
How many lobes does the left lung have?
Two: Upper, lower
What separates the lobes of the lungs?
Deep indentations called fissures
What does the horizontal fissure separate?
The right upper and right middle lobes
What does the right oblique fissure separate?
The right middle and right lower lobes
What does the left oblique fissure separate?
The left upper and left lower lobes
What is the cardiac notch?
A groove in the left upper lobe where the heart sits
What is the apex of the lung?
The top portion that sits above the clavicle
What is the base of the lung?
The bottom portion resting on the diaphragm
What muscle is responsible for ventilation and supports the lung base?
The diaphragm
What surrounds each lung?
serous membranes
What are the two layers of the pleura?
Parietal pleura and visceral pleura
What is the pleural cavity?
The space between the pleural membranes
What is found in the pleural cavity?
Pleural fluid
What is the function of pleural fluid?
Reduces friction and allows lungs to change shape during ventilation
How does air reach the alveoli?
Through passageways of the respiratory tract
What are the two regions of the respiratory system?
Upper respiratory tract and lower respiratory tract
What structures are in the upper respiratory tract?
Passages from the nasal cavity to the larynx
What structures in the lower respiratory tract?
Passages from the trachea to the alveoli
What are the two functional zones of the respiratory system?
Conducting zone and respiratory zone
What is the function of the conducting zone?
Carries air to structures where gas exchange occurs
Does gas exchange occur in the conducting zone?
No
What is the function of the respiratory zone?
Gas exchange
Where is the respiratory zone located?
In the lungs (alveoli)
Where does the conducting zone begin?
At the nasal cavity
What are the functions of the conducting zone?
Warms, filters, and humidifies incoming air
Through which structures does air first enter the respiratory system?
Through the nares/nostrils into the nasal cavity
What are three main functions of the nasal cavity?
Filters, warms, and humidifies inhaled air
After the nasal cavity, where does air travel?
The pharynx/throat
What are the three divisions of the pharynx?
Nasopharynx, oropharynx, and laryngopharynx
What is the function of the soft palate and uvula?
They move upward during swallowing to close off the nasopharynx
What can happen if the soft palate mechanism fails?
Food or liquid may enter the nasal cavity
Where is the nasopharynx located?
Posterior to the nasal cavity
Where is the oropharynx located?
Posterior to the oral cavity
What passes through the oropharynx?
Both food and air
Where is the laryngopharynx located?
Between the larynx and esophagus
What passes through the laryngopharynx?
Both food and air
Where does air go after the pharynx?
Into the larynx, or voice box
What structure prevents food from entering the larynx?
The epiglottis
What happens to the larynx during swallowing?
It moves upward and the epiglottis seals it off
What is the largest cartilage of the larynx?
The thyroid cartilage
What is another name for the thyroid cartilage?
Adam’s apple
What structure carries air from the larynx downward?
The trachea
What type of cartilage supports the trachea?
C shaped rings of hyaline cartilage
Where does the trachea split?
At the carina
What does the trachea divide into?
The right and left primary bronchi
What do primary bronchi branch into?
Secondary bronchi (one per lung lobe)
What comes after secondary bronchi?
Tertiary bronchi, then smaller branches
What are the smallest conducting airways called?
Bronchioles
What marks the end of the conducting zone?
Terminal bronchioles
What begins the respiratory zone?
Respiratory bronchioles
What structures are found at the ends of bronchioles?
Alveolar sacs
What are alveoli shaped like?
Grape like clusters
What surrounds alveoli?
Pulmonary capillaries
What supplies blood to the alveoli?
Pulmonary arteries
What drains blood from the alveoli?
Pulmonary veins
What is the respiratory membrane?
The site of gas exchange between air and blood
Why are alveoli ideal for gas exchange?
They have thin walls and a large surface area with rich blood supply
How is pulmonary ventilation defined?
The physical movement of air into and out of the lungs
What is pulmonary gas exchange and where does it occur?
Diffusion of gases across the respiratory membrane between alveoli and pulmonary capillaries
Define gas transport in the blood stream
Movement of oxygen and carbon dioxide through the blood
What is tissue gas exchange?
Diffusion of gases between systemic capillaries and body tissues
How does airflow direction relate to pressure differences?
Air moves from areas of higher pressure to lower pressure
State Boyle’s law
Pressure and volume are inversely proportional
What happens to pressure when lung volume increases?
Pressure decreases
What happens to pressure when the lung volume deceases?
Pressure increases
Why does increasing lung volume allow air to enter the lungs?
Because intrapulmonary pressure drops below atmospheric pressure, causing air to flow in
Which muscles are primarily responsible for inspiration?
The diaphragm and external intercostal muscles
What role does the diaphragm play during inspiration?
It contracts and flattens, increasing thoracic cavity volume
Which accessory muscles assist during forced inspiration?
Sternocleidomastoid, pectoralis major and minor, serratus anterior, and scalene muscles.
Name at least three accessory inspiratory muscles
Sternocleidomastoid, Serratus anterior, and scalene muscles.
Is expiration usually active or passive? Why?
Passive, because it relies on elastic recoil of the lungs
What happens to intrapulmonary pressure during inspiration?
It decreases below atmospheric pressure
What happens when intrapulmonary pressure is lower than atmospheric pressure?
Air flows into the lungs
What happens to the intrapulmonary pressure during expiration?
It increases above atmospheric pressure
When does air leave the lungs in terms of pressure differences?
When intrapulmonary pressure is higher than atmospheric pressure
How do thoracic cavity dimensions change during inspiration?
They increase in height and diameter
What changes occur in lung volume during inspiration?
Lung volume increases
What changes occur in lung volume during expiration?
Lung volume deceases
How does elastic recoil contribute to expiration?
It returns the lungs to their original size, pushing air out
What are pulmonary volumes?
The amounts of air exchanged during breathing
What instrument is used to measure lung volumes?
A spirometer
Define tidal volume
The amount of air inhaled or exhaled during normal breathing
What is the normal tidal volume in a healthy adult?
About 500 mL
Define expiratory reserve volume
The amount of air that can be forcibly exhaled after a normal exhalation