The Digestive System

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A comprehensive set of flashcards covering the key vocabulary and concepts of the digestive system.

Last updated 7:08 PM on 4/4/26
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100 Terms

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Digestion

The process by which food substances are changed into forms that can be absorbed through cell membranes.

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Gastrointestinal (GI) tract

Also known as the alimentary canal; a continuous tube from mouth to anus through which food passes.

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Ingestion

The act of taking food into the digestive tract.

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Propulsion

The movement of food through the GI tract, including swallowing and peristalsis.

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Secretion

The release of water, acid, buffers, and enzymes into the lumen of the GI tract.

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Mechanical digestion

The physical breakdown of food, including chewing and mixing with saliva.

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Chemical digestion

The enzymatic breakdown of food into simpler molecules.

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Absorption

The uptake of digested nutrients from the intestinal cells into the bloodstream.

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Defecation

The elimination of indigestible substances from the body as solid waste (feces).

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Mucosa

The innermost lining of the GI organs, consisting of epithelium and connective tissue.

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Submucosa

Layer of areolar connective tissue that contains blood vessels and nerve plexuses.

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Muscularis externa

Layer composed of smooth and skeletal muscles; responsible for peristalsis and segmentation.

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Serosa

Outer layer of the GI tract made of connective tissue and simple squamous epithelium.

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Salivary glands

Glands that secrete saliva; include parotid, submandibular, and sublingual glands.

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Teeth

Structures in the mouth that mechanically break down food during chewing.

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Tongue

Muscular organ that aids in mixing food and initiating swallowing.

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Pharynx

Throat; the passageway for food to the esophagus and air to the larynx.

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Esophagus

The muscular tube that conveys food from the pharynx to the stomach.

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Stomach

The J-shaped organ that stores and digests food.

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Duodenum

The first part of the small intestine, where the majority of digestion occurs.

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Jejunum

The middle section of the small intestine where absorption occurs.

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Ileum

The final section of the small intestine before it joins the large intestine.

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Cecum

The beginning of the large intestine, where the appendix is attached.

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Colon

Part of the large intestine containing ascending, transverse, descending, and sigmoid regions.

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Rectum

The final section of the large intestine, leading to the anus.

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Gallbladder

The organ that stores and concentrates bile produced by the liver.

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Liver

The organ responsible for metabolic regulation, blood filtration, and bile production.

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Pancreas

An accessory organ that secretes enzymes and buffers into the small intestine.

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Cholecystokinin (CCK)

A hormone that stimulates the gallbladder to contract and release bile.

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Secretin

A hormone that stimulates the pancreas to secrete bicarbonate and liver to produce bile.

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Gastric Juice

A mixture of acids and enzymes secreted by the stomach for digestion.

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Intrinsic factor

A glycoprotein required for the absorption of vitamin B12 in the intestine.

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Cirrhosis

A chronic liver disease caused by excessive alcohol consumption or viral infection.

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Hepatitis

Inflammation of the liver, often caused by viral infections.

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Bile

A digestive fluid produced by the liver that helps emulsify fats.

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Haustra

Pouches in the large intestine that allow for expansion and contraction.

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Peristalsis

Waves of muscular contractions that move food through the digestive tract.

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Mas Peristalsis

A strong peristaltic wave that drives contents of the colon into the rectum.

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Dysphagia

Difficulty swallowing, could be due to various health issues.

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Diarrhea

Excessively watery stool resulting from rapid passage through the intestines.

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Constipation

Difficulty in passing stool or infrequent bowel movements.

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Bristol Stool Chart

A medical aid to classify the form of human feces into seven categories.

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Colitis

Inflammation of the colon, sometimes caused by infections.

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Irritable bowel syndrome

A common disorder affecting the large intestine, characterized by abdominal pain.

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Filiform papillae

Tongue structures that provide roughness and friction.

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Fungiform papillae

Tongue structures scattered across the surface that contain taste buds.

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Circumvallate papillae

Large V-shaped structures at the back of the tongue that contain taste buds.

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Foliate papillae

Structures located on the lateral aspects of the posterior tongue.

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Lingual frenulum

A fold of tissue that attaches the tongue to the floor of the mouth.

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Bolus

A rounded mass of food ready to be swallowed.

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Esophageal sphincter

Muscle that controls the passage of food from the esophagus to the stomach.

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Pyloric sphincter

Muscle that regulates the passage of chyme from the stomach to the small intestine.

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Enzymatic breakdown

The process by which enzymes convert complex molecules into simpler forms.

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Hydrolysis

A chemical process that splits molecules by adding water.

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Nucleic acids

Biomolecules that are essential for all known forms of life, involved in genetic information.

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Electrolytes

Ions that are essential for various bodily functions, including fluid balance and nerve function.

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Lacteals

Lymphatic capillaries in the small intestine that absorb dietary fats.

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Goblet cells

Cells in the intestinal epithelium that secrete mucus.

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Paneth cells

Cells in the intestine that secrete antimicrobial molecules such as lysozyme.

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Ascitic fluid

Fluid that accumulates in the abdominal cavity, often due to liver dysfunction.

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Insulin

A hormone produced by the pancreas that regulates blood sugar levels.

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Metabolism

The process by which the body converts food into energy.

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Vagus nerve

A cranial nerve that controls various functions, including digestion.

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Metabolic regulation

The process by which the liver regulates the production and breakdown of substances.

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Phagocytosis

The process by which cells ingest or engulf other cells or particles.

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Hepatic lobules

The functional units of the liver, involved in detoxification and metabolism.

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Cystic duct

Duct that connects the gallbladder to the common bile duct.

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Cholecystitis

Inflammation of the gallbladder, often related to gallstones.

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Biliary calculi

Gallstones; solid particles that form from bile cholesterol and bilirubin.

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Glucose

A simple sugar that is an important energy source in living organisms.

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Glycogen

The storage form of glucose in the liver and muscles.

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Peptidase

An enzyme that breaks down peptides into amino acids.

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Articulatory system

The system involved in the formation of speech sounds.

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Absorptive phase

The phase in which nutrients are absorbed following a meal.

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Post-absorptive phase

The phase after absorption, characterized by the use of stored nutrients.

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Vitamin storage

The liver’s function of storing vitamins needed by the body.

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Detoxification

The process by which the liver removes or neutralizes toxins.

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Fat emulsification

The process by which bile breaks down fat into smaller droplets for digestion.

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Appendix

A small, tube-like structure attached to the cecum, often considered vestigial.

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Histamine

A compound involved in local immune responses and regulation of gastric acid.

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Gastric acid

The digestive fluid produced in the stomach, primarily composed of hydrochloric acid.

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Electrolyte imbalance

A disturbance in the balance of electrolytes in the body, often affecting function.

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Dietary fiber

Plant-based carbohydrates that are poorly digested but beneficial for digestive health.

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Chyme

Partially digested food mixed with gastric juices, moving from the stomach to the small intestine.

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Antigen presentation

The process by which immune cells present foreign substances to T-cells.

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Feces

The solid waste product eliminated from the digestive tract.

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Hydration

The process of absorbing or retaining water in bodily tissues.

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Mucosal lining

The protective layer of the gastrointestinal tract that facilitates absorption and secretion.

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Buccal Phase

Phase of swallowing where bolus is compressed against the hard plate; the tongue then pushes it into the oropharynx.

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Pharyngeal Phase

Phase were the swallowing reflex is stimulated by the uvula; medulla triggers muscular contractions; bolus passes over the epiglottis

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Esophageal Phase

Bolus is pushed toward the stomach; peristalsis moves the bolus through the esophagus into the stomach.

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Gastric Villi

Gastric pits/glands that secrete gastric juice. They increase the surface area for absorption.

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Cephalic Phase

The phase that occurs before food enters the stomach; duration = minutes; triggers vagus nerve and stimulates gastric secretions and motility.

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Gastric Phase

The phase of digestion when food enters the stomach, stimulating gastric secretions and contractions. It lasts several hours and is primarily regulated by neural and hormonal mechanisms.

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Intestinal Phase

The phase of digestion that occurs when chyme enters the small intestine, promoting further digestive secretions and nutrient absorption. It is mediated by both hormonal and nervous signals.

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Pancreatic Amylase

An enzyme produced by the pancreas that breaks down carbohydrates into simple sugars, facilitating digestion in the small intestine.

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Pancreatic Lipase

An enzyme produced by the pancreas that aids in the digestion of lipids (fats) in the small intestine by breaking them down into fatty acids and glycerol.

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Proteolytic enzymes

enzymes that break down proteins into smaller peptides and amino acids during digestion.

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Nucleases

are enzymes that hydrolyze nucleic acids (DNA and RNA) into smaller nucleotides, facilitating their digestion in the small intestine.

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Inflammatory Bowl Disease

inflammation of the large and sometimes small intestines