Breast pathology: malignant

arise from the supportive connective tissue and grows rapidly

sarcoma

• arise from the epithelium in the ductal or glandular tissue.

• usually has speculations

• SONO: irregular margins and shadowing from calcifications

carcinoma

carcinoma cancer is classified by?

originating location and tendency to spread

that is the earliest form of breast caner?

Ductal carcinoma in situ (DCIS) AKA intraductal carcinoma

• noninvasive

• 100% cure rate usually

Ductal carcinoma in situ

SONO: ductal carcinoma in situ

calcifications and ductal enlargement

accounts for 80% if breast cancers (MC)

invasive ductal carcinoma (infiltrating ductal carcinoma)

invasive ductal carcinoma (IDC)

begin in the duct and invade the fatty tissue of the breast and metastasize via the blood stream or lymphatic system

Invasive lobular carcinoma (ILC)

AKA: lobular carcinoma; 2nd mc type of invasive tumor

• begin in the lobule and invade the fatty tissue of the breast and metastasize via the blood stream

• poorer prognosis than IDC, invasive ductal carcinoma

triple-negative breast cancer

• does not have any of the receptors that are commonly found in breast cancer

  • female hormone: estrogen, progesterone

  • protein called human epidermal growth factor (HERZ)

inflammatory breast cancer

• rare and very aggressive (spreads within 3-6mths)

• accounts for 1% of all breast cancer in the US per the American cancer society

inflammatory breast cancer affects women at what age?

younger than 40

s/s: inflammatory breast cancer

• breast enlargement

• discoloration

• pain/tenderness

• inward nipple

• rash, itchy

Paget’s Disease

• arises in the retroaerolar ducts and grows in the direction of the nipple

• rare

s/s of pagets disease

rash-like, crusty, scaly appearance of the nipple

Paget’s disease affects women of?

over 50

sono: Paget’s disease

• retroarolar mass within irregular margins

• heterogenous internal echoes

• attenuation with posterior shadowing