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Research Study Question
One clear, well-defined question the study is designed to answer
Specific Aims
Clearly defined actions that help move the study toward its goal
SMART Aims
Specific, Measurable, Attainable, Relevant, Timely
Conceptual Framework
A model using boxes/arrows showing relationships studied
Directed Acyclic Graph (DAG)
A diagram using nodes and arrows to show hypothesized causal pathways
Theoretical Framework
Established models from literature used to guide study design and interpretation
Health Belief Model
Framework explaining health behavior based on beliefs about risk and benefits
Theory of Planned Behavior
Framework stating behavior is influenced by intention, attitudes, and social norms
Social Cognitive Theory
Framework emphasizing learning through observation and environment
Health Outcome
Any measurable disease, disability, condition, attitude, marker, or health state
Exposure
A factor that varies across populations and may affect outcomes
Operationalize
Turning a concept into something measurable
Examples of Physical Activity Outcomes
Minutes of moderate activity per week; steps per day
Examples of Diet Outcomes
Healthy Eating Index; ounces of sugary drinks per week
Examples of Sleep Outcomes
Sleep quality; hours of sleep
Examples of Mental Health Outcomes
Perceived stress; depression diagnosis
Societal-Level Exposure
Factors affecting society broadly (minimum wage, rent control)
Community-Level Exposure
Factors affecting communities (public transportation, air pollution)
Individual-Level Exposure
Factors affecting individuals (insurance status, employment)
Kitchen Sink Approach
Testing many variables without theory, leading to meaningless associations
Dead Salmon Study
Example showing false positives can occur when many tests are run
Voxel
Small unit of the brain measured in fMRI scans
Statistically Significant
A result unlikely due to chance alone
Hypothesis
Prediction based on the research question
Primary Hypothesis
Main prediction being tested
Secondary Hypothesis
Additional prediction explored after the main one
Case Series
Study describing a group of people with the same disease or condition
Cross-Sectional Study
Study measuring exposure and disease status at one point in time
Case-Control Study
Compares past exposures between diseased cases and healthy controls
Cohort Study
Follows groups with different exposures over time for new disease cases
Correlational (Ecological) Study
Compares average exposure and disease levels across populations
Experimental Study
Researchers assign intervention or control groups
Qualitative Study
Explores perceptions, experiences, and meanings
Review Study
Summarizes existing literature
Meta-Analysis
Combines statistical results from multiple studies
Primary Study
Collecting and analyzing new data
Secondary Study
Analyzing existing collected data
Tertiary Study
Reviewing already collected/analyzed research
Observational Study
Researcher observes without assigning exposure
Descriptive Study
Describes who, what, when, where
Analytic Study
Tests relationships between exposure and outcome
Experimental Study
Always analytic because it tests intervention effects
EDP
Exposure, Disease, Population focus of a study
Case Report
Description of one person with a disease or unusual condition
Case Definition
Inclusion/exclusion criteria used to classify cases
Inclusion Criteria
Conditions required to join a study
Exclusion Criteria
Conditions preventing participation
Data Abstraction Form
Tool used to standardize data collected from records
Case Fatality Rate (CFR)
Proportion of people with a disease who die from it
Proportionate Mortality Rate (PMR)
Proportion of deaths due to a specific cause
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