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Carbon dioxide (CO2)
The waste product of metabolism expelled from the body during exhalation.
Exhalation
The physiological process during which CO2 is expelled from the body.
Blood Brain Barrier
A barrier that CO2 is capable of crossing to enter the cerebrospinal fluid.
Cerebrospinal fluid
The location where CO2 combines with water to produce carbonic acid.
Carbonic acid
The substance formed in the cerebrospinal fluid when CO2 and water combine.
Hydrogen ions
Particles formed when carbonic acid separates in the cerebrospinal fluid.
pH
The measurement of the concentration of hydrogen ions in a solution.
Blood gases
Substances such as O2, CO2, and bicarbonate (HCO3) that are controlled by the pH.
Bicarbonate (HCO3)
One of the substances that must be in balance with the pH.
Normal pH range
A tight balance between 7.35 and 7.45.
7.35
The lower limit of the normal pH range of the body.
7.45
The upper limit of the normal pH range of the body.
Arterial level of CO2
Its changes result in a corresponding change in the pH of the cerebrospinal fluid.
Medulla
The anatomical structure near which chemical chemoreceptors are located.
Chemical chemoreceptors
Sensory receptors responsible for regulating respiratory function and monitoring arterial CO2.
Respiratory function
A term referenced in the transcript as a synonym for breathing.
Increased arterial CO2 level
Leads to an increase in the depth and rate of respirations (breathing faster).
Breathing faster
A result of increased depth and rate of respirations due to high CO2.
Increased O2 outcome
Leads to a reduction in the arterial CO2 level.
Reduced depth and rate
The respiratory result of increased O2 levels which cause breathing to slow down.
Breathing slows
A physiological response to increased O2 levels.
COPD
Chronic Obstructive Pulmonary Disease; a condition where patients live with higher CO2 and lower O2 levels.
93-95\text{%}
An oxygen level that is not unusual for a patient with COPD.
Chronic increased CO2 levels
A long-term condition found in COPD patients that the body becomes accustomed to.
COPD Compensation
The body increases respirations and depth to create balance between O2 and CO2.
pH Balance Goal
The body's constant attempt to return the pH back to the range of 7.35−7.45.
Crackles
Lung sounds heard in a field with fluid in the small airway; formerly called Rales.
Rales
The older clinical term used for the lung sounds now referred to as crackles.
Small airway fluid
The cause of crackles heard during lung auscultation.
Inspiration
The phase of breathing during which crackles are heard.
Fine crackles
Lung sounds that resemble the sound of rolling hair between your fingers.
Rolling hair between fingers
The characteristic auditory description of fine crackles.
Coarse crackles
Lung sounds described as sounding like ripping velcro apart.
Ripping velcro
The characteristic auditory description of coarse crackles.
Wheezes
Lung sounds produced by a narrow airway or air sac affecting O2 and CO2 exchange.
Inspiratory wheezes
Wheezes occurring when a narrow air sac does not allow air to enter.
Narrow air sac
The physiological state of the alveoli that causes inspiratory or expiratory wheezes.
Alveoli
The clinical term for air sacs in the lungs.
Expiratory wheezes
Wheezes occurring when narrowing of the air sac prevents air from getting out.
Sibilant wheezes
Wheezes distinguished by high pitched and shrill sounds.
Rhronci
A lung sound differentiated from sibilant wheezes by pitch (spelled as in transcript).
High pitched and shrill
The specific auditory qualities of sibilant wheezes.
Asthma
One of several conditions that causes narrowed airways.
Congestive heart failure (CHF)
A cardiovascular condition that can cause narrowed airways.
Heart failure (HF)
A condition listed as a cause of airway narrowing.
Chronic bronchitis
A chronic lung