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Which of the following best describes a primary function of the kidneys?
Regulating water, ion balance, and excreting wastes
Which structure directly transports urine from the kidney to the bladder?
Ureter
The kidneys are located:
Retroperitoneal between T12 and L5
The right kidney sits slightly lower than the left because:
The liver crowds it
The fibrous capsule of the kidney functions to:
Prevent spread of infection
The renal hilum is:
The entry/exit site for vessels, ureter, and nerves
The renal cortex is:
The superficial granular region
Renal pyramids are located in the:
Medulla
The tip of a renal pyramid is called the:
Papilla
Urine flows from the papilla into the:
Minor calyx
Which structure collects urine from multiple minor calyces?
Major calyx
The renal pelvis drains into the:
Ureter
Blood enters the kidney through the:
Renal artery
The correct arterial flow order begins with:
Renal artery → segmental artery
The afferent arteriole:
Brings blood into the glomerulus
The efferent arteriole:
Carries blood away from the glomerulus
The glomerulus is:
A capillary tuft for filtration
The parietal layer of the glomerular capsule is made of:
Simple squamous epithelium
The visceral layer consists of:
Podocytes
Filtrate collects in the:
Capsular space
The proximal convoluted tubule is characterized by:
Microvilli and high reabsorption
The nephron loop primarily functions to:
Concentrate urine
The distal convoluted tubule:
Has few microvilli and functions in secretion
Collecting ducts:
Receive filtrate from many nephrons
Once filtrate reaches the collecting duct:
It is considered urine
Cortical nephrons:
Make up ~85% and are mostly in cortex
Juxtamedullary nephrons:
Have long loops important for concentrating urine
The vasa recta are:
Capillaries associated with juxtamedullary nephrons
Peritubular capillaries:
Surround cortical nephrons and aid reabsorption
The filtration membrane allows passage of:
Water and small solutes but not proteins
The three layers of the filtration membrane include:
Fenestrated endothelium, basement membrane, podocytes
Glomerular filtration is:
Passive and driven by hydrostatic pressure
Net filtration pressure (NFP) is:
About 10 mm Hg outward
Hydrostatic pressure in glomerular capillaries is:
The main force pushing filtrate out
The juxtaglomerular apparatus (JGA):
Regulates GFR and blood pressure
Granular (JG) cells:
Secrete renin
Macula densa cells:
Detect NaCl concentration in filtrate
High NaCl at macula densa causes:
Afferent arteriole constriction
Low NaCl at macula densa causes:
Dilation of afferent arteriole and renin release
Tubuloglomerular feedback:
Adjusts GFR based on NaCl levels
The renin-angiotensin-aldosterone system (RAAS):
Increases blood pressure
Sympathetic stimulation causes:
Constriction of afferent arterioles
Glomerular filtration rate (GFR):
~180 L/day filtered
Only about how much urine is produced daily?
~1.5 L
Tubular reabsorption:
Returns substances from filtrate to blood
Tubular secretion:
Moves substances from blood to filtrate
Transcellular reabsorption occurs:
Through tubule cells
Paracellular reabsorption occurs:
Between cells
The urinary bladder contains:
Transitional epithelium (urothelium)
The detrusor muscle:
Contracts to expel urine
The trigone is:
Area with ureter openings in bladder
The prostatic urethra:
Passes through prostate
The membranous urethra:
Passes through urogenital diaphragm
The spongy urethra:
Passes through penis
Anuria is:
Extremely low urine output