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Thiamin
B1
Riboflavin
B2
Niacin
B3
Thiamin RDA
male- 1.2 mg/d & female- 1.1mg/d
Riboflavin RDA
male- 1.3mg/d & female- 1.1mg/d
Niacin RDA
male- 16mg/d & female- 14mg/d
Vit B6 RDA
1.3mg
Iodine RDA
150 ug/d
Thiamin UL
NO UL
Riboflavin UL
No UL
Niacin UL
35 mg/d
Vit B6 UL
100mg
Iodine UL
1100ug/d
Thiamin dietary sources
Meat (pork), green veggies (peas, asparagus, okra), whole/enriched/fortified grains, legumes, yeast, wheat germ
Riboflavin dietary sources
green veggies, whole/enriched grains, milk/dairy, legumes. light sensitive!
Niacin dietary sources
Meat (fish), enriched grain products, cereals, legumes, coffee + tea
Vitamin B6 dietary sources
meat/fish/poultry, starchy veggies, non-citrus fruit (bananas), nuts, cereals
Iodine dietary sources
seafood, seaweed, iodized salt, milk (iodophores used on utters), bread (dough conditioners)
thiamin toxicity
NONE!
riboflavin toxicity
NONE!
niacin toxicity
flushing, hepatotoxicity, itchy skin, heart burn, nausea, liver damage
Vitamin B6 toxicity
sensory + peripheral neuropathy, unsteady gate, parethesia, impaired tendon reflexes
Iodine toxicity
Increase TSH, hypothyroidism risk, Grave’s Disease, thyroid adenomas/thyroiditis, weight loss, increase heat production, tachycardia, muscular tremor, irritability, nervousness, exophthalmos.
how is most thiamin transported
in RBCs as TPP
how is riboflavin transported
bound to albumin or globulins
most flavoproteins are
oxidizing agents (accept pair of e- + 2H+
2 structures of niacin
Nicotinamide + Nicotinic Acid
population at risk for niacin
malabsorptive disorders, corn based diet, sorghum based diet
thyroid hormone synthesis, iodide is transported ___ into thyroid cells via ___
actively, Na+
how is niacin transported
primarily as nicotinamide in the blood
how is B6 transported
albumin
how is iodine transported
binding proteins, tight binding, slow turnover