essay 31 - functional manifestation of liver disease - jaundice, portal hypertension, ascites

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Last updated 5:27 PM on 6/14/26
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8 Terms

1
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what is jaundice

yellow discolouration of the skin, sclera and mucous membranes due to hyperbilirubinemia (serum bilirubin > 2-2.5 mg/dL)

2
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describe pre-hepatic jaundice (hemolytic) and give pathogenesis

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3
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describe intra-hepatic jaundice (hepatocellular) and give pathogenesis

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4
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describe post-hepatic jaundice (obstructive/cholestatic) and give pathogenesis

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what is portal hypertension

  • sustained increase in portal venou pressure, usually >12 mmHg (normal ~5-10 mmHg)

6
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describe portal hypertension

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what is ascites

  • a pathological accumulation of fluid in the peritoneal cavity, most often due to portal hypotension in cirrhosis

8
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describe ascites

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