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infection
a disease or condition caused by a microorganism
incubation period
time between infection and onset of symptoms
chain of infection
1. Susceptible host: has factors that influence the risk of infection
2. Infectious agent: pathogen, such as bacteria or virus
3. Reservoir: where the organism survives, such as in a human
4. Portal of exit: how the organism leaves, such as via blood
5. Mode of transmission: how it spreads, such as direct contact
6. Portal of entry: how it enters a new host, such as broken skin
virulence
speed and intensity which a pathogen can cause an infection
epidemic
widespread outbreak of a disease that affects many people
viruses
· Unable to reproduce on its own
· Can only replicate inside another organism’s cell
· Do not usually survive long outside of host
bacteria
· Speed of replication varies from 20 min to 2 weeks
· Can enter a dormant stage where they can survive for years
physical barriers
· Skin is first line of defense
· Nasal passages and ear canals protected by hair
· Lungs protected by cough reflex and cilia
chemical barriers
· Saliva breaks down bacteria
· Stomach acid difficult for organisms to survive
· Vagina is slightly acidic, discouraging bacteria growth
immune system
protects body against pathogens
innate immune system
boys natural ability to protect
acquired immune system
built up from exposure to pathogens
acute inflammatory response
initial reaction to tissue damage, brings blood to injury site
vaccine
preparation of weakened or killed microorganisms administered to confer immunity
controllable risk factors
· Balanced diet
· Sleep
· Exercise
· Stress
uncontrollable risk factors
· Age
· Genetics
autoimmune disease
immune system mistakenly identifies part of the body as nonself
antibiotic
a drug that works by killing or preventing the growth of bacteria
antibiotic resistance
ability of bacteria to adapt and grow in presence of antibiotics
global infectious diseases
· Diarrhea
· Tuberculosis
· Malaria
HIV/ AIDS
Rapid weight loss, Cough, Night sweats, Diarrhea, Rashes or skin blemishes, Memory loss no cure |
Chlamydia
Painful urinations, Genital discharge, Infertility, Ectopic pregnancy antibiotics |
Gonorrhea
Inflammation, Painful urination, Thick genital discharge antibiotics |
pelvic inflammatory disease
Pain in lower abdomen, Abnormal vaginal discharge, Chills, Pain during sex antibiotics |
human papillomavirus
causes genital warts and is linked to cancers such as cervical, anal, penile, and throat cancer. Many people have no symptoms. no cure |
genital herpes
Causes painful blisters or sores around the genitals or rectum, itching, burning, and flu-like symptoms during outbreaks. no cure |
hepatitis
Causes inflammation of the liver, which may lead to fatigue, nausea, abdominal pain, jaundice, dark urine, and in severe cases liver damage or liver failure. either antibiotics or no cure |
cardiovascular disease
leading cause of death in US
coronary heart disease
most common type of CVD
atherosclerosis
thickening or hardening of arteries due to buildup
CHD
atherosclerosis of coronary arteries
ischemia
insufficient oxygen to tissue
myocardial infarction
heart attack
coronary thrombosis
blockage of coronary artery by blood clot
angina
chest pain
arrhythmia
abnormal heartbeat
normal heartbeat
60-100 bpm
sudden cardiac arrest
loss of heart function
ventricular fibrillation
ventricles contract erratically, causing heart to tremor
stroke or cerebrovascular accident (CVA)
blood flow to brain is blocked
ischemic stroke
cause by blockage in blood vessel in brain
hemorrhagic stroke
rupture blood vessel which leads to brain bleeding
transient ischemic attacks (TIA)
ministrokes or periods of restricted blood supply
congestive heart failure
heart doesn’t pump blood as it should, fluids build up in lungs
normal blood pressure
<120, <80
elevated blood pressure
120-120, <80
hypertension stage 1
130-139, 80-89
hypertension stage 2
>140, >90
diabetes
metabolic disorder in which production or use of insulin is disrupted
type 1
pancreas produces little or no insulin
type 2
bodys cells become resistant to insulin
cancer
uncontrolled growth of cells
most new cases of cancer
breast cancer for women, prostate cancer for men
most deaths
lung cancer
stem cells
undifferentiated cells that can give rise to specialized cells
carcinogen
cancer causing substance
oncogene
gene that drives a cell to grow
tumor
mass of extra tissue
benign
slow growth, unlikely to spread
malignant
capable of spreading to surrounding tissues
metastasis
cancer that has spread from one part of the body to another r
stage 0
cancer in situ (only in layer of cells where it began)
stage 1
small and localized
stage 2 and 3
locally advanced, may involve lymph nodes
stage 4
metastasized to distant sites
carcinoma
arise from epithelial tissue
sarcoma
arise in connective tissue
lukemia
cancer of blood or bone marrow
lymphoma
originate in lymph nodes or glands
risk factors for cancer
· Family history
· Lifestyle factors
· Social and economic factors
· Environmental factors
cancer treatments
· Surgery
· Chemotherapy
· Radiation
skin cancer ABCDE
Asymmetry
Border irregularity
Color variation
Diameter larger than ¼ inch
Evolving
unintentional injuries
those that are not purposefully inflicted
leading cause of unintentional injury
motor vehicle accidents
violence
use of force or threat of force to inflict intentional injury, physical or psychological
assault
attack by one person on another using force or threat of force to inflict injury
hazing
actions taken to cause mental or physical discomfort, embarrassment or ridicule in individuals seeking to join an organization
hate speech
acts that convey a grossly negative view of persons based on gender, ethnicity, religion, sexual orientation or disability
sexual assault and coercion
sexual assault is any sexual behavior forced on someone without their consent
statutory rape
sexual intercourse with someone under the age of consent
the red zone
a period of time when female students are at greatest risk
sexual harassment
person of authority or suggestive language
stalking
malicious following, harassing or threatening of one person by another
cyberstalking
use of electronic media to pursue, harass or contact another person who has not solicited the contact
cyberharrassment
tormenting emails, instant messages, blog entries and website entries
cyberbullying
amongst children and college students
deepfake
artificial intelligence software used to create realistic fake videos and pictures that mimic a targets voice, facial expressions and mannerisms