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Flashcards covering key concepts related to monoclonal antibodies and their production.
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What type of cells are fused to create hybridoma cells in monoclonal antibody production?
A tumour cell is fused with a B cell.
What is the purpose of fusing a tumour cell with a B cell?
To create a hybridoma cell that has the properties of both cells.
What is a hybridoma cell?
A new cell formed from the fusion of a B cell and a tumour cell, capable of rapid division and producing specific antibodies.
What is a key property of B cells that is utilized in making monoclonal antibodies?
B cells produce specific antibodies.
What are plasma cells derived from?
B-lymphocytes.
What does the term 'antigen' refer to in the context of monoclonal antibodies?
A substance that induces an immune response, typically recognized by antibodies.
Why are hybridoma cells beneficial in the production of monoclonal antibodies?
They divide rapidly and produce specific antibodies.