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Charles Nelson
professor of pediatrics @ Harvard Medical School & Boston Children’s Hospital
Izidor Ruckel
a child who experienced the abuse & neglect of the Romanian government instituted orphanages
had polio (disease that can lead to paralysis due to muscle weakness)
w/ surrogate mother: treated Ruckel w/ love, care, kindness, set foundation for secure attachment style but was disrupted b/c of placement in Romanian orphanage after mother’s death
w/ adoptive parents: disorganized attachment style due to the environment he endured in the Romanian orphanage, aggressive & avoidant
Romanian orphanage
government institution for “irrecoverable” children that neglected/abused said children, society (inside said orphanage) was like a prison, “dog eat dog” world
results of children kept in the Romanian orphanages
stunted growth & problems concerning their mental & emotional health
Nelson observations/deductions (of said children): strange behaviors/coping mechanisms, desperate/needy for attention due to extensive neglect, acting warm then acting cold (disorganized attachment style w/ others), symptoms of problems w/ brain development
the 4 attachment styles
secure: feelings of trust & safety within relationship, stability (built through healthy relationship w/ caregiver)
anxious: fear of abandonment, strong need for reassurance, discomfort w/ too much independence (built through unhealthy relationship w/ caregiver)
avoidant: tendency to avoid emotional closeness, dismissive of importance of intimacy within relationships (built through unhealthy relationship w/ caregiver)
disorganized: mix of anxious & avoidant, fear of close relationships, inconsistent & hard-to-predict behavior, seeking love then angered when love is given (built through unhealthy relationship w/ caregiver)
brain development
for positive development: love, attention, care from caregivers, healthy parenting or healthy parental figure in life
for negative development: neglect, abuse from caregivers, unhealthy parenting or no healthy parental figure in life
EEG
electroencephalography
measures electrical activity of brain
result of EEG in Romanian orphans: 40-watt light bulb instead of 100-watt light bulb (abnormally low)
MRI
magnetic resonance imaging
studies anatomy of brains/highlight where electrical brain activity occurs using images
results of MRI on Romanian orphans: significant reduction in gray and white matter, meaning brains were physically smaller than the average brain
Nim Tottenham
associate professor of psychology @ the University of LA in CA
held experiment involving children from orphanages & their amygdalae when seeing unfamiliar people or their adoptive mothers
results of experiment: no difference in amgydalae’s emotional response between the strangers & mothers
brain rewiring
ability of the brain in order to compensate for negative development caused by a negative environment
stress response
survival mechanism of the body in dire situations, also known as “fight-or-flight”
long-term effects: impairs health/takes toll on body, contributes to high blood pressure, artery-clogging deposits’ formation, brain changes associated w/ mental health disorders & obesity
steps/order: 1. eyes/ears, 2. brain, 3. amygdala, 4. hypothalamus, 5. autonomic nervous system, 6. adrenal glands
amygdala
receives info from eyes/ears, conducts emotional processing, interprets images & sounds, sends distress signal to hypothalamus if danger is detected
hypothalamus
command center, communicates w/ rest of body thru autonomic nervous system
direct of release of hormones in the pituitary gland
part of HPA axis
autonomic nervous system
controls involuntary body functions, non-skeletal muscles & organs, has 2 components (sympathetic and parasympathetic)
sympathetic nervous system
“gas pedal,” triggers fight-or-flight (burst of energy provided for body during danger)
increased heartrate & respiration, suppressed digestion (uses energy)
parasympathetic nervous system
“brake,” promotes “rest & digest” (calms body down after danger)
counterbalances sympathetic nervous system, return to normal homeostasis slowly (conserve energy)
adrenal glands
part of HPA axis
receives signals from autonomic nerves, responds by pumping epinephrine (hormone) into the bloodstream
release adrenaline & noradrenaline, which release cortisol
epinephrine
triggers release of blood sugar/glucose & fats from temporary storage sites
HPA axis
consists of the Hypothalamus, Pituitary gland, & Adrenal glands
2nd component of stress response system, relies on hormonal stress signals to repress the sympathetic nervous system
techniques to counter stress
relaxation response = happens automatically, but can do manually through deep abdominal breathing, focus on soothing word(s), yoga, tai chi, vice versa
physical activity = exercise
social support = people one can go to for advice or comfort
the 4 thinking styles
concrete sequential (cs)
abstract sequential (as)
abstract random (ar)
concrete random (cr)
concrete = register info directly w/ 5 senses, dealing w/ the obvious/”here and now,” not looking for hidden meanings or relationships between ideas/concepts, “it is what it is”
abstract = visualize/conceive ideas, understand/believe that which one cannot actually see, using intuition & imagination, looking beyond “what is,” “it is not always what it seems”
sequential = mind organizes info in a linear, step-by-step manner, one follows a logical train of thought, traditional approach to dealing w/ info, preference of plan & following it rather than being impulsive
random = mind organizes info in chunks & in no particular order, one may skip steps in procedure & still achieve desired result, may start in middle, end, or work backwards, preference of impulsivity
neuron communication
neurons at rest
action potential/impulse travels through pre-synaptic neuron to its axon terminal
vesicles fuse w/ cell membrane of pre-synaptic neuron’s axon terminal & release neurotransmitters into synapse
released neurotransmitters are received by post-synaptic neuron’s receptors
as neurotransmitters are received by post-synaptic neuron’s receptors, action potential/impulse also travels through to the post-synaptic neuron (carried by neurotransmitters)
post-synaptic neuron’s receptors send back the neurotransmitters into the synapse, then neurotransmitters are degraded by enzymes in the synapse and then are received by pre-synaptic neuron’s transporters and stored back into vesicles
physiological psychology
biological basis of behavior
CAT scans/CT
computed tomography
x-rays, cross-sectional, different angles
apply @ bone, lung, chest, cancer
FMRI
functional magnetic resonance imaging
same as MRI, but shows electrical activity as it is taking place, as it’s “live”
nervous system
made up of 2 parts = central & peripheral
central: brain & spinal cord
peripheral: nerves, 5 senses
brain
interprets sensory info & generates response(s), processing center for thoughts, motives, & emotions
spinal cord
central pathway of info, nerves (neuron bundles) to (afferent) & from (efferent) the brain & the peripheral nervous system
afferent
to
efferent
from
reflexes
quick & involuntary responses w/ the brain
peripheral nervous system
all nerve cells (not brain & spine)
consists of somatic nervous system & autonomic nervous system
somatic nervous system
voluntary movement, large skeletal muscles
pituitary gland
part of HPA axis
release ACTH hormone to adrenal glands
“master gland”
5 hormones to remember
adrenaline
ghrelin
leptin
melatonin
oxytocin
endocrine system
collection of glands that regulates bodily functions through the release of hormones (HPA axis)
brain evolution
3 main parts of the brain = forebrain, midbrain, hindbrain
brain develops from bottom to top
hence hindbrain is the simplest and earliest part, & forebrain is the most complex and latest part
forebrain
consists of the cerebral cortex, lobes, & limbic system
cerebral cortex
large, sets humans from other mammals, lots of neurons, most advanced, outer layer/surface, location of language, complex skills, problem-solving, social skills
folds allow cortex to develop within skull
areas of cortex = sensory, motor, association
sensory cortex: receives sensory input
motor cortex: sends out motor info/movement
association cortex: associates info in sensory & movement cortices
dysfunctions
apraxia = can’t organize movement
agnosia = can’t recognize sensory input
alexia = can’t read
agraphia = can’t write
forebrain lobes
frontal (higher-level thought) = problem-solving, planning, judgement
parietal (somatosensory/touch) = input from sensory receptors (pressure, pain, temperature)
temporal (auditory) = speech, processing, music
occipital = sight
Paul Broca’s area
brain damage in left hemisphere in stroke victims result in the inability to speak
Carl Wernicke’s area
left temporal lobe, stroke damage resulted in receptive aphasia (can’t comprehend speech)
cerebral hemispheres
corpus collosum: band of nerve fibers connecting the hemispheres
Roger Sperry: split brain experiment, severed collosum for seizure patients, resulted in the inability to draw objects but still be able to see them
contralateral processing: info crosses between hemispheres, left to right/right to left
hemispherical specialization theory
the concept that one is more left-brained or more right-brained
limbic system
consists of thalamus, hippocampus, amygdala, hypothalamus
thalamus: relays sensory info (not smell) to cerebral cortex
hippocampus: processes memory
amygdala: emotional processing
hypothalamus: regulation of temperature, sex drive, food, & water intakes (pituitary)
lateral = on switch for eating
ventromedial = off switch for eating
midbrain
consists of colliculi, basal ganglia, ventral tegmental area (VTA)
inferior colliculus
auditory tracking, is below superior colliculus (refer to name)
superior colliculus
visual tracking, is above inferior colliculus (refer to name)
basal ganglia
motor movement
ventral tegmental area (VTA)
reward system
tectum
roof of midbrain, just above the colliculi
tegmentum
floor of midbrain
hindbrain
lowermost part of the brain, contains pons, medulla, cerebellum
pons
body movement
medulla
controls heart rate & breathing
cerebellum
coordinate voluntary movement, balance
neurons
are the foundation of the nervous system, receive & transmit info, & are consisted of 3 parts
neuron parts
cell body/soma
dendrites (send & receive info)
axon (carry info away from cell body/soma)
axon terminal (end of road)
myelin: insulates/speeds up info carry, jumps between nodes of Ranvier (gaps)
neuron communication
action potential/nerve impulse travels through
dendrite
cell body
axon
axon terminal
synapse
outside the neuron, space between axon terminal (pre) & dendrite (post)
vesicles
storage, stores neurotransmitters (pre)
transporters
reuptake, receives back neurotransmitters (pre)
enzymes
in the synapse, degrades neurotransmitters
receptors
receive & release (post)
neurotransmitters
carry action potential, chemicals
excitatory effect
increases activity, doesn’t always cause action, inside charges of ions during effect are positive (depolarization)
inhibitory effect
decreases activity, probability of action goes down, inside charges of ions are negative (hyperpolarization)
way to remember hyperpolarization = hibernation sounds like hyperpolarization
ion movement during action potential
positive (+) ions move inside
negative (-) ions move outside
increase of (+) inside
ions move down w/ axon
myelin effect
animation (resting potential)
acetylcholine (ACh/ACTH)
function: enables muscle action, learning, memory
malfunctions: w/ Alzheimer’s, ACTH producing neurons rot
dopamine
functions: influences movement, learning, attention, emotion
malfunctions: oversupply linked to schizophrenia, undersupply linked to tremors & decreased mobility w/ Parkinson’s
serotonin
functions: affects mood, hunger, sleep, arousal
malfunctions: undersupply linked to depression
norepinephrine
functions: helps control & alertness
malfunctions: undersupply can depress mood
GABA (gamma-aminobutyric acid)
functions: major inhibitory neurotransmitter
malfunctions: oversupply linked to seizures, tremors, insomnia
glutamate
functions: major excitatory neurotransmitter
malfunctions: oversupply can overstimulate brain & produce migraines or seizures
endorphins
functions: influence the perception of pain or pleasure
malfunctions: oversupply w/ opioid drugs can suppress body’s natural endorphin supply
substance p
functions: involved in pain perception & immune response
malfunctions: oversupply can lead to chronic pain