Ch. 8: Nonneoplastic Diseases of Bone

abnormal and disordered production of cementum and bone

does not have same context as epithelial dysplasia

dysplasia

most common type of cemento-osseous dysplasia

teeth are vital

can involve more than one tooth

older lesions ar eprimarily radiopaque

periapical cemento-osseous dysplasia

Periapical cemento-osseous dysplasia is more prevalent in…

women than men

black women

older than 30 years old

typically in the posterior mandible area

isolated, well delineated radiopaque to radiolucent lesion

less than 1.5 cm in size

reveals gritty pieces of soft and hard tissue within the lesion

focal cemento-osseous dysplasia

extensive form that presents as multiple lobulated masses

most often in the posterior area in one or more quadrants

florid cemento-osseous dysplasia

developmental disease

classic radiographic appearance (ground glass)

characterized by replacement of bone with abnormal connective tissue with varying amounts of calcium

surgical treatment (recontouring) most likely recommended

fibrous dysplasia

most common type of fibrous dysplasia (85%)

characterized by involvement of single bone

may lead to malocclusion, tipping, or displacement of adjacent teeth

monostotic fibrous dysplasia

monostotic fibrous dysplasia that involves maxilla and surrounding bones

craniofacial fibrous dysplasia

involvement of more than one bone

may be associated with cafe au lait spots, jaffe type, and albright syndrome

polyostotic fibrous dysplasia

characterized by endocrine abnormalities such as precocious puberty or skeletal growth deformities

associated with cafe au lait spots

albright syndrome

metabolic bone disease - serum alkaline phosphatase is elevated

mosaic bone due resorption and deposition of bone

loss of lamina dura radiographically

“cotton wool” appearance radiographically

possible transformation into osteosarcoma

paget’s disease

osteitis deformans

may present as multilocular radiolucency

microscopically can resemble lesion caused by hyperparathyroidism

common feature is divergence in roots of the teeth

central giant cell granuloma

pseudocyst consisting blood filled spaces surrounded by multinucleated giant cells and fibrous connective tissue

aneurysmal bone cyst

when in young children caused by deficiency of vitamin D is called rickets

delayed tooth eruption and periodontal disease

in adults may be associated with malabsorption syndrome, liver, or kidney disease

osteomalacia