Gut-Brain Peptides (Long-term)

What is the main role of long-term gut-brain peptides?

govern average caloric intake and energy expenditure over weeks to years

Where is leptin secreted from?

adipocytes

What is leptin’s level proportional to?

fats stores in the body

What is the main function of leptin?

informs brain on how much body fat we have

What can happen in obesity related to leptin?

Leptin levels becomes dysregulation with signaling appetite to the brain

Where is insulin secreted from?

Pancreatic beta (β) cells

What is one main metabolic function of insulin?

stimulate glucose uptake by body cells

What storage processes does insulin promote?

glycogen and fat synthesis

How does insulin relate to appetite regulation?

has receptors in the brain and acts like leptin as an index of body fats stores

Compared to leptin, insulin has what effect on appetite?

Weaker effect