7 - Anticoag Dosing
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31 Terms
Lovenox vs Heparin to start out with
Lovenox
DVT PPx, hip/knee replacement
Lovenox
DVT PPx, abdominal surgery
Lovenox
DVT Tx
Lovenox
MI / Unstable angina / Thrombolytic adjunct / PCI
Lovenox Dosage Forms
prefilled syringes → will use all of it in one go
graduated prefilled, multi-dose vial → must know mg per # mL (might give calculation question)
Lovenox SQ Injection Instructions
SQ Injection Instructions
Patient lying down
Do NOT expel air bubbles from prefilled syringes
Use abdomen fatty tissues (LOVEnox → LOVE Handles) → switch sites left and right anterolateral and posterolateral abdominal wall
Inject in 90 degree angle (not the usual 45 degree)
Heparin DVT/PE Tx
Good choice when need anticoag that works the fastest
IV (treatment), SC for prophylaxis
Treatment
Heparin lock only for maintaining open IV, not for anticoag
10 units/mL for infants <10 kg
100 units/mL for everyone else
Heparin DVT/PE PPx
Prophylaxis
usually used for DVT prophylaxis in pregnant patients (usu other options)
5,000-10,000 units Q8-12h
Rotate sites just like any other SQ
Pradaxa
Nonvalvular Afib
PO capsules: 75, 110, 150 mg
Pradaxa
Treatment of DVT and PE
PO capsules: 75, 110, 150 mg
Pradaxa
Reduction of Risk Recurrence of DVT/PE
PO capsules: 75, 110, 150 mg
Pradaxa
PPx of DVT/PE after hip replacement
PO capsules: 75, 110, 150 mg
Factor Xa Inhibitors
Dosage Forms
Rivaroxaban also comes as oral suspension
Arixtra
DVT PPx
dosed regardless of weight
Arixtra
DVT/PE Tx
Arixtra
Fondaparinux (Arixtra)
Store at room temp
Xarelto
Stroke PPx Afib
Xarelto
DVT/PE Tx
Xarelto
DVT PPx
Xarelto
VTE PPx start inpatient
Xarelto
Decrease Risk of CV events in patients with CAD or PAD
Xarelto
Rivaroxaban (Xarelto)
Andexaneta alfa (Andexxa) stays in fridge
Eliquis
Apixaban (Eliquis)
DC before surgery: 1 day if low risk, 2 days if high risk
Savaysa
Non-valvular A fib
Savaysa
DVT/PE
Dalteparin
Dalteparin: 2500-5000 mg units SC QD
Clopidogrel
Cloidogrel: 300-600 mg loading dose then 75 mg QD
Prasugrel
Prasugrel: 60 mg loading, then 10 mg QD (5 mg QD if <65 kg)
Ticagrelor
Ticagrelor: 180 mg then 90 mg BID
Dipyridamole
Agrenox
Dipyridamole: QID with water 1 hr before meals
Aggrenox: 1 cap BID