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What are the 5 layers of the skin?
(From deep to superficial)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum (only in palms and soles of feet)
Stratum Corneum
What causes osteoporosis?
Deficiency of calcium
What hormone is released when CA levels are too high?
Calcitonin (*Think "can tone it down")
What hormone(s) is released when CA levels are too low?
Parathyroid & Calcitriol
Whats the difference between Appositional growth & Epiphyseal growth?
Appositional grows in width
Epiphyseal grows in length
What do ligament do?
Attach bone to bone
What do tendons do?
Attach bone to muscle
What is bone formation called?
Osteogenesis
What happens when growing stops?
Epiphyseal plate ossifies
What is ossification?
Hardening
The metatarsophalangeal joint is associated with what small bone?
Sesamoid bone (ex Patella)
What part of bone do tendons & ligaments attach to?
Periosteum
What vessels can be found in Haversian & Volkmann's canals?
Artery, Vein, & Lymph
What does the matrix of spongy bone look like?
Open network of trabeculae
What is 1/3 of Osseous tissue composed of?
CA ions
What type of bone cell resides in endosteum?
Osteoclasts
What are osteocytes?
Most common cell in bone
Where are osteocytes held?
In the Lacunae
What is the process when mesenchyme cells differentiate?
Intramembranous ossification
How does the osteoid matrix differ from bone?
It doesn't have CA ions yet
Where is the primary center of ossification located?
Diaphysis during development
What is not a function of skeletal muscles?
Store lipids (Adipose cells do this)
Muscle cells are packed with which protein filaments?
Myofibrils
Cytoplasm in animal cells is ____________ in a muscle cell.
Sarcoplasm
Sarcomeres are found in all except?
Smooth muscle (It is not striated like other muscles)
What elastic structure pulls myosin back to "normal"?
Titin filaments
What fibrous joints are on the ends of the tibia & fibula?
Syndesmoses
What type of joint sutures are mostly immovable?
Fibrous
What is true about synovial joints?
Separated by fluid-containing joint cavity
What is not true about synovial fluid?
Reduces friction & contains phagocytic cells
What is not a type of synovial joint?
Sealed joint
What type of joint is in costal cartilage of 1st rib & manubrium of sternum?
Synchondroses
What structure of a synovial joint is a band-like ligament?
Reinforcing ligament
(ex Knee joint)
All influence the stability of synovial joints except?
Bursae
What joint is multiaxial w/ a hemispherical head?
Ball & socket
What synovial joint movement where 2 surfaces slide past each other?
Gliding
Bursitis is caused by?
Friction & Fall on knee
Arthroplasty is?
Replacement of a diseased joint with prothesis
PCL prevents tibia from sliding in which direction?
Backwards
ACL prevents tibia from sliding which direction?
Forwards
What fibrous joint is where the tooth is in a bony socket?
Gomphoses
Where is cartilaginous symphysis articulation?
Between the pubic bone
Do osetocytes divide?
No
What do osteoblasts do?
Perform osteogenesis & build bone
What do osteoclasts do?
Breakdown bone matrix
What are osteoprogenitor cells?
Stem cells that undergo mitosis (Pre-Osteoblasts)
What is step 1 & 2 of Integument repair?
Bleeding occurs & Mast cells trigger an inflammatory response
What is step 3 & 4 of Integument repair?
A scab stabilizes & protects area then fibroblasts produce scar tissue
What is step 5 & 6 of Integument repair?
Inflammation decreases, clot disintegrates and fibroblasts strengthen scar tissue
What is the final step of Integument repair?
A raised keloid forms
What is inflammatory response?
Germinative cells migrate around the wound, Maccrophages then clean the area, and fibroblats and endothelial cells produce granulation tissue
What do your sebaceous glands (Holocrine) do?
Produce oil
(Lubricant for skin & kills bacteria)
What do you Ceruminous glands (Apocrine) do?
Creates sticky cerumen (earwax)
What do the mammary glands (Apocrine) do?
Secrete milk
What are the 2 types of seat glands?
Eccrine & Apocrine
What does the Eccrine (Merocrine) sweat gland do?
Cools skin
(Found in palms, soles of feet, & forehead)
What is sweat released by?
Exocytosis
What do Apocrine (Merocrine) sweat glands do?
Secretes fatty acids, proteins, and sexual scent through normal sweating
(Found in armpits and anogenital areas)
What are the 4 tissue types?
Epithelial
Connective
Muscular
Nervous/Neural
What tissue type is in the mammary glands, sweat glands, & salivary gland duct?
Stratified epithelium
Glandular epithelium has which 2 types of glands?
Endocrine & Exocrine
What do Enodcrine glands secrete?
Hormones
What do Exocrine glands secrete?
Sweat tears, & oil
What is the mode of secretion in Apocrine glands?
Secrete by shedding cytoplasm
(Mammary glands)
What is the mode of secretion in Merocrine glands?
Secretes by exocytosis in vesicle
(Most seat glands & salivary glands)
What is the mode of secretion in Holocrine glands?
Fill up, rupture, & die
(sebaceous glands)
Which direction to Haversian canals go?
Vertical
Which direction does Volkmann's Canals go?
Perpendicular to central canal
(sideways/horizontal)
What are Mesenchymal cells?
Stem cells that respond to injury or infection & differentiate into fibroblasts, macrophages, etc.
What do Mast cells do?
Stimulate inflammation after injury or infection; Release histamine or heparin (Basophils)
What does Reticular connective tissue do?
Provides support & Forms stroma of lymphoid organs
(Lymph nodes, Sleen, Liver, & bone marrow)
What is an immovable joint?
Synarthroses
(ex Sutures in skull)
What is a slightly movable joint?
Amphiarthroses
(ex Intervertebral discs, ribs)
What are freely movable joints?
Diarthroses
(ex Shoulder, hips, knees, elbow, etc.)