Endocrine Drugs

Glucophage

metformin hydrochloride

Actos

pioglitazone hydrochloride

Type 2 diabetes mellitus

Amaryl

glimepiride

Sulfonylurea

Type 2 diabetes mellitus

Glucotrol

glipizide

type 2 diabetes mellitus

Micronase or DiaBeta

glyburide

Januvia

sitagliptin phosphate

Type 2 diabetes mellitus

Janumet

metformin hydrochloride/sitagliptin phosphate

Biguanide/DPP-4 inhibitor

Type 2 diabetes mellitus

Combination

Victoza

liraglutide

Type 2 diabetes mellitus

Ozempic/Wegovy

semaglutide

GLP-1 receptor agonistM

Mounjaro/Zepbound

tirzepatide

GLP-1 and GIP

Humalog

insulin lispro

insulin

diabetes mellitus

Novolog

insulin aspart

insulin

diabetes mellitus

Humulin R

insulin NPH

Novolin R

regular insulin

insulin

diabetes mellitus

Humulin N

insulin NPH

Novolin N

NPH insulinL

Lantus

insulin glargine

insulin

diabetes mellitus

Levemir

insulin detemir

insulin

diabetes mellitus

Armour Thyroid

thyroid

hypothyroidism

Synthroid

levothyroxine

hyperthyroidism

Fosamax

alendronate

osteoporosis

Calcimar
Miacalcin

calcitonin

osteoporosis

Glucovance

glyburide/metformin

NIDDM

Metaglip

glipizide/metformin

NIDDM

Avandamet

rosiglitazone/metformin

NIDDM

Actoplus Met

pioglitazone/metformin

NIDDM

Melatonin

gland: pineal gland

• circadian rhythm

Growth Hormone

gland: anterior pituitary

• cell growth

• under:

  • dwarfism

• over:

  • gigantism → kids

  • acromegaly → adults

Antidiuretic hormone

gland: posterior pituitary

• water balance

• under:

  • diabetes insipidus (DI: dried inside)

  • dehydration, polyuria, thirst

• over:

  • SIADH (Syndrome of Inappropriate Antidiuretic Hormone)

  • increase in H2O (more water than sodium → hyponatremia)

T3/T4

gland: thyroid

• metabolism

• under:

  • hypothyroidism = myxdema

  • low energy; low HR & NP

  • Hashimotos: long, slow Sx, sluggish metabolism

• over:

  • hyperthyroidism

  • high energy; high HR & BP

  • Graves’ Disease: high, hot Sx

Calcitonin

gland: thyroid

• lowers blood Ca

Parathyroid Hormone (PTH)

gland: parathyroid = calcium

• increases blood calcium

• under:

  • hypothyroidism

  • hypocalcemia (low Ca)

  • high phosphorus

• over:

  • hyperparathyroidism

  • hypercalcemia (high Ca)

  • low phosphorus

Insulin

gland: pancreas

• lowers blood sugar

Glucogon

gland: pancreas

• raise blood sugar

Glucocorticoids

gland: adrenal cortex

• anti-inflammatory

• under:

  • Addison’s disease

  • low ACTH (adrenocorticotropic hormone)

  • weakness, low BP, skin darkening

• over:

  • Cushing’s disease

  • high ACTH

    • weight gain, high BP

Epinephrine

gland: adrenal medulla

• fight or flight

Estrogen

gland: ovaries

• female s-x characteristics

Testosterone

gland: testes

• male s-x characteristics